Enhanced Behavioral Intervention to Improve Long-Term Weight Loss in Young Adults

加强行为干预以改善年轻人的长期减肥效果

• 批准号: 7706688
• 负责人: John M Jakicic
• 金额: $ 74.99万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-20 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7706688
• 关键词: Achievement; Address; Adherence; Age-Years; Behavior Therapy; Behavioral; Body Composition; Body Weight; Body Weight decreased; Body fat; Cardiovascular Diseases; Chronic; Development; Diabetes Mellitus; Dietary intake; Energy Intake; Energy Metabolism; Enhancement Technology; Evaluation; Exercise; Feedback; Goals; Individual; Instruction; Intervention; Intervention Studies; Link; Malignant Neoplasms; Measures; Methods; Monitor; Motivation; Musculoskeletal; Obesity; Outcome; Overweight; Physical activity; Physiological; Prevalence; Public Health; Randomized; Self Efficacy; Technology; Text; Time; Weight; Weight maintenance regimen; abstracting; age group; behavior change; effective intervention; expectation; fitness; improved; programs; psychosocial; response; weight loss intervention; young adult

DESCRIPTION (provided by applicant): This application is in response to RFA-HL-08-007 "Targeted Approaches to Weight Control for Young Adults". As outlined in the RFA, this application will focus on development, refinement, and evaluation of a behavioral approach to weight control in young adults, with the focus of this application being on enhancing long-term weight loss. Consistent with the RFA, young adults for this application are defined as individuals 18-35 years of age. The prevalence of obesity in young adults has been increasing, and excessive body weight have been linked to numerous chronic conditions including cardiovascular disease, diabetes, many forms of cancer, and numerous musculoskeletal problems. The focus of this application is to develop and evaluate interventions that may be appropriate for young adults to improve weight loss outcomes following a 24 month intervention. Therefore, the primary aim of this study is to examine whether an enhanced weight loss intervention (EWLI) that includes technology components results in improved weight loss in young adults (18-35 years of age) compared to a standard behavioral weight loss intervention (SBWP) over a period of 24 months. Additional aims include examination of these interventions on changes in body composition, body fat distribution, fitness, physical activity, dietary intake, and behavioral/psychosocial measures that may be predictive of behavior change. Assessments will occur at 0, 6, 12,18, and 24 months. This study involves the recruitment of 480 overweight and obese young adults (18-35 years of age). Subjects will participate in a 24 month behavioral weight loss program that includes a reduction in energy ntake and moderate-to-vigorous intensity exercise (progressively increasing from 100 to 300 minutes per week). Subjects will be randomized to receive this intervention (SBWP) or this intervention in combination with technology enhancements (EWLI). EWLI will receive daily text messaging prompts to reinforce adherence to the behavioral intervention from months 7-24, and will wear a monitor from months 13-24 that provides real-time feedback on energy expenditure and achievement of daily physical activity goals. It is hypothesized that these technology enhancements to EWLI will significantly improve weight loss, body composition, body fat distribution, fitness, physical activity, and dietary intake compared to SBWP. RELEVANCE (See instructions): Obesity rates of young adults have significantly increased and the ability to sustain weight loss long-term in this age group has been less than desirable. Therefore, there is a need to develop and implement effective intervention initiatives to address this public health concern, which is the focus of this proposed intervention study. (End of Abstract)

描述（由申请人提供）：本申请是对RFA-HL-08-007“针对年轻人的体重控制方法”的回应。正如RFA中所概述的那样，该申请将专注于开发，完善和评估年轻人体重控制的行为方法，该申请的重点是加强长期减肥。与RFA一致，本申请的年轻人定义为18-35岁的个体。肥胖在年轻人中的流行率一直在增加，体重过重与许多慢性疾病有关，包括心血管疾病、糖尿病、多种形式的癌症和许多肌肉骨骼问题。本申请的重点是开发和评估可能适合年轻人的干预措施，以改善24个月干预后的减肥结果。因此，本研究的主要目的是检查与标准行为减肥干预（SBWP）相比，包括技术成分的增强减肥干预（EWLI）是否会在24个月内改善年轻人（18-35岁）的体重减轻。其他目的包括检查这些干预措施对身体成分、体脂分布、健身、体育活动、饮食摄入量和行为/心理社会措施的变化，这些措施可能预测行为变化。将在0、6、12、18和24个月时进行评估。这项研究招募了480名超重和肥胖的年轻人（18-35岁）。受试者将参加为期24个月的行为减肥计划，包括减少能量摄入和中等至剧烈强度的运动（每周从100分钟逐渐增加到300分钟）。受试者将随机接受该干预（SBWP）或该干预联合技术增强（EWLI）。EWLI将收到每日短信提示，以加强从7-24个月的行为干预的坚持，并将从13-24个月佩戴监测器，提供关于能量消耗和日常身体活动目标实现的实时反馈。据推测，与SBWP相比，EWLI的这些技术增强将显著改善体重减轻、身体组成、体脂分布、健身、体育活动和饮食摄入。相关性（参见说明）：年轻人的肥胖率显著增加，这一年龄组长期保持减肥的能力不太理想。因此，有必要制定和实施有效的干预措施，以解决这一公共卫生问题，这是这项拟议干预研究的重点。(End摘要）