Neural correlates of cognitive biases in social phobia

社交恐惧症认知偏差的神经相关性

• 批准号: 7217000
• 负责人: Jason Scot Moser
• 金额: $ 2.96万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-25 至 2008-09-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7217000
• 关键词: adolescence (12-20); behavioral /social science research tag; bias; choice; clinical research; cognition; emotions; evoked potentials; face expression; human subject; major depression; neural information processing; phobias; predoctoral investigator; psychological tests; psychomotor reaction time; psychopathology; psychophysiology; social adjustment; vocabulary; young adult human (21-34)

DESCRIPTION (provided by applicant): The long-term objective of the current research proposal is to provide a foundation of knowledge on the neural correlates of cognitive biases in social phobia in order to better inform clinically relevant issues such as nosology, diagnostics, treatment, and prevention. As a first major step towards achieving this long-term goal, the aims of the current study involve applying knowledge from experimental psychophysiology and cognitive science to the investigation of cognitive biases in adult psychopathology. Specifically, the current study aims are to utilize event-related brain potentials (ERPs) to examine cognitive biases implicated in the development and maintenance of social phobia and to identify those biases that are specific to social phobia (SP) by comparing them to those present in patients with major depressive disorder (MDD), as data suggest social anxiety and depression may manifest in similar ways, but the underlying cognitive mechanisms may be different. This will be accomplished by recording attentional allocation and response monitoring ERPs while patients with SP, patients with MDD and normal control participants perform two speeded reaction time tasks.

描述（由申请人提供）：当前研究提案的长期目标是提供关于社交恐惧症认知偏见神经相关性的知识基础，以便更好地告知临床相关问题，如疾病分类学，诊断，治疗和预防。作为实现这一长期目标的第一个重要步骤，目前的研究的目的涉及应用实验心理生理学和认知科学的知识，在成人精神病理学的认知偏见的调查。具体来说，目前的研究目的是利用事件相关脑电位（ERP）来检查与社交恐惧症的发展和维持有关的认知偏差，并通过将社交恐惧症（SP）与重度抑郁症（MDD）患者中存在的偏差进行比较来识别社交恐惧症（SP）特有的偏差，因为数据表明社交焦虑和抑郁可能以类似的方式表现，但潜在的认知机制可能不同。这将通过记录注意力分配和反应监测ERP来完成，同时SP患者、MDD患者和正常对照参与者执行两个加速反应时任务。