The Structure of PTSD Comorbidity in the Axis II Domain

描述（由申请人提供）：研究表明，精神病理学的广泛类别是沿着沿着称为内化和外化的正交维度组织的。因子分析工作表明，这些基于气质的潜在因素解释了主要精神障碍的表现、严重程度和共病性。最近的研究已经将这一模型扩展到创伤领域，提供了证据表明这些维度可能类似地解释了创伤后应激障碍（PTSD）的共病模式。这项关于PTSD共病结构的研究仅限于共病轴I障碍的研究，并且主要是描述性分析。因此，本横断面研究的目标是使用多变量分析技术，更充分地研究的内在和外在结构的创伤后应激障碍共病的轴II域和调查的气质因素，预测表型表达的共病在一个样本中的250名男性和女性的创伤后应激障碍。这样做将为PTSD共病的简约、维度概念化提供支持，并将精神疾病结构理论扩展到创伤和轴II精神病理学领域。

DESCRIPTION (provided by applicant): Research suggests that broad classes of psychopathology are organized along orthogonal dimensions termed internalizing and externalizing. Factor analytic work demonstrates that these temperament-based latent factors account for the expression, severity, and comorbidity in major mental disorders. Recent studies have extended this model into the realm of trauma, providing evidence that these dimensions may similarly account for patterns of comorbidity in posttraumatic stress disorder (PTSD). This work on the structure of PTSD comorbidity is limited to the study of comorbid Axis I disorders and by largely descriptive analyses. Therefore, the goal of the present cross-sectional study is to use multivariate analytic techniques to more fully examine the internalizing and externalizing structure of PTSD comorbidity in the Axis II domain and to investigate the temperament factors that predict the phenotypic expression of this comorbidity in a sample of 250 men and women with PTSD. Doing so will provide support for a parsimonious, dimensional conceptualization of PTSD comorbidity and extend theory on the structure of mental illness into the realms of trauma and Axis II psychopathology.