Characterization of the evolutionary rules governing phage receptor binding protein

控制噬菌体受体结合蛋白的进化规则的表征

• 批准号: 2735267
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2735267
• 关键词: Characterization; evolutionary; rules; governing; phage

The project aims to leverage advancements in automation and computational methods to investigate several fundamental questions of phage biology and protein binders. This is envisioned to be a highly interdisciplinary project where automation and insights into molecular biology will allow the production of a large amount of high-quality data from which several important biological insights can be extracted. The biological insights will be in the realms of fundamental phage biology, evolutionary theory, and protein biophysics. We believe those insights will have a broad range of applications in fields such as phage therapy, protein engineering and directed evolution.BBSRC priority areas:- Understanding the rules of life- Transformative technologies

该项目旨在利用自动化和计算方法的进步来研究噬菌体生物学和蛋白质结合剂的几个基本问题。这被设想为一个高度跨学科的项目，其中自动化和对分子生物学的见解将允许产生大量高质量的数据，从中可以提取几个重要的生物学见解。生物学见解将涉及基础噬菌体生物学、进化理论和蛋白质生物物理学领域。我们相信这些见解将在噬菌体治疗、蛋白质工程和定向进化等领域有广泛的应用。BBSRC优先领域：-了解生命的规则-变革性技术