Core--Patient registry

核心项目是该方案的核心资源。它包括五个核心单位，负责执行以下工作：（a）病人登记，负责识别、筛选和将受试者纳入登记，以及中央数据库和数据管理，以便在筛选/诱导和慢性阶段进行神经解剖分析;（c）在筛选/诱导和慢性阶段进行基本神经心理学研究;（d）按不同项目的需要进行统计分析;（e）监察所有与受试者保密、知情同意程序、数据质量和研究进展有关的事项。这些操作对于我们计划中涉及人类的所有研究的执行至关重要，并将持续进行。在方案期间，这些措施在各个方面都得到顺利执行，在即将到来的供资期内保持不变。该计划的研究人员还继续开发新技术，以提高神经解剖学和神经心理学数据收集和分析的质量。因此，新产品现在可用于该研究小组和其他人的认知神经科学研究（例如，单通道组织分割、标准解剖空间中的三维病变分析（MAP-3技术））。

The Core project is the central resource of the Program. It encompasses five Core Units, which carry out the following operations: (a) Patient Registry, which regards the identification, screening and induction of subjects into the Registry, and the central Database and data management for neuroanatomical analysis at both the screening/induction and chronic stages; (c) performance of basic neuropsychological studies at the time of screening/induction and at the chronic stage; (d) statistical analysis as needed by different projects; (e) monitoring of all matters pertaining to subject confidentiality, informed consent procedures, data quality and research progress. These operations, which are essential for the execution of all studies in our Program involving humans, are carried on continuously. They have been carried out smoothly, in all aspects, for the duration of the Program, and remain unchanged for the forthcoming funding period. The investigators in the Program have also continued to develop new techniques required to improve the quality of neuroanatomical and neuropsychological data gathering and analysis. As a result, new products are now available, to this research group and to others, for cognitive neuroscience research (e.g., single-channel tissue segmentation, 3- dimensional lesion analysis in a standard anatomical space (the MAP-3 technique)).