Core B- Animal Core

动物核心将为患者提供材料（数据科学发射器）和手术服务 用于长期测量大鼠和小鼠平均动脉压、心率和运动活动的仪器。日常护理、代谢数据收集、数据科学系统的数据采集和制表也将成为核心的职责，以及补充分析，例如日间血压和心率变异性测定。为这些动物植入微型渗透泵也将是核心的职责。 该核心还将为所有研究人员提供慢性病的材料和手术服务 静脉输注、重复动脉血采样和平均动脉的长期测量 大鼠的压力和心率。可用于遥测研究的相同计算机数据收集和补充分析也将适用于这些大鼠。

The animal core will provide materials (Data Sciences transmitters) and surgical service for instrumentation of rats and mice for chronic measurement of mean arterial pressure, heart rate, and motor activity. Daily care, metabolic data collection, and data acquisition and tabulation from the Data Sciences systems also will be a responsibility of the core, as well as supplemental analyses such as diurnal blood pressure and heart rate variability determinations. Implantation of these animals with osmotic minipumps also will be the responsibility of the core. The core also will provide to all investigators the materials and surgical service for chronic intravenous infusion, repeated arterial blood sampling, and chronic measurement of mean arterial pressure and heart rate in rats. The same computerized data collection and supplemental analyses available for the telemetry studies also will be available for these rats.