Core B- Animal Core

动物核心将提供材料(数据科学发射器)和外科服务 用于长期测量平均动脉压、心率和运动活动的大鼠和小鼠的仪器。数据科学系统的日常护理、新陈代谢数据收集、数据采集和制表也将是核心的一项责任，以及补充分析，如昼夜血压和心率变异性测定。将这些动物植入渗透性微泵也将是核心的责任。 中心还将为所有研究人员提供慢性阻塞性肺疾病的材料和手术服务 静脉输液，重复动脉采血，慢性测量平均动脉 大鼠的血压和心率。同样可用于遥测研究的计算机化数据收集和补充分析也将适用于这些大鼠。

The animal core will provide materials (Data Sciences transmitters) and surgical service for instrumentation of rats and mice for chronic measurement of mean arterial pressure, heart rate, and motor activity. Daily care, metabolic data collection, and data acquisition and tabulation from the Data Sciences systems also will be a responsibility of the core, as well as supplemental analyses such as diurnal blood pressure and heart rate variability determinations. Implantation of these animals with osmotic minipumps also will be the responsibility of the core. The core also will provide to all investigators the materials and surgical service for chronic intravenous infusion, repeated arterial blood sampling, and chronic measurement of mean arterial pressure and heart rate in rats. The same computerized data collection and supplemental analyses available for the telemetry studies also will be available for these rats.