Core B- Animal Core

核心B-动物核心

• 批准号: 7063187
• 负责人: Michael W. Brands
• 金额: $ 25.55万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7063187
• 关键词: angiotensin /renin /aldosterone hypertension; animal care; biomedical facility; blood flow measurement; blood pressure; data collection methodology /evaluation; drug delivery systems; heart rate; laboratory mouse; laboratory rat; surgery; surgery material /equipment

The animal core will provide materials (Data Sciences transmitters) and surgical service for instrumentation of rats and mice for chronic measurement of mean arterial pressure, heart rate, and motor activity. Daily care, metabolic data collection, and data acquisition and tabulation from the Data Sciences systems also will be a responsibility of the core, as well as supplemental analyses such as diurnal blood pressure and heart rate variability determinations. Implantation of these animals with osmotic minipumps also will be the responsibility of the core. The core also will provide to all investigators the materials and surgical service for chronic intravenous infusion, repeated arterial blood sampling, and chronic measurement of mean arterial pressure and heart rate in rats. The same computerized data collection and supplemental analyses available for the telemetry studies also will be available for these rats.

动物核心将为以下患者提供材料（Data Sciences发送器）和手术服务： 用于长期测量平均动脉压、心率和运动活动的大鼠和小鼠的仪器。日常护理，代谢数据收集以及数据科学系统的数据采集和制表也将是核心的责任，以及补充分析，如昼夜血压和心率变异性测定。这些动物的渗透微型泵植入也将是核心的责任。 中心还将为所有研究者提供慢性胰腺炎的材料和手术服务。 静脉输注、重复动脉采血和长期测量平均动脉压 大鼠的血压和心率。用于遥测研究的相同计算机化数据收集和补充分析也将适用于这些大鼠。