Emotion Regulation Therapy for Generalized Anxiety

广泛性焦虑的情绪调节疗法

• 批准号: 7091039
• 负责人: RICHARD G HEIMBERG
• 金额: $ 22.07万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7091039
• 关键词: anxiety disorders; behavioral /social science research tag; clinical research; clinical trials; cognitive behavior therapy; emotional adjustment; handbook; human subject; human therapy evaluation; patient oriented research; psychotherapy; therapy design /development

DESCRIPTION (provided by applicant): Generalized Anxiety Disorder (GAD) is characterized by excessive, uncontrollable worry and significant central nervous system arousal. It is prevalent, chronic, and associated with significant functional impairment (now recognized as comparable to major depressive disorder). Cognitive-behavioral therapies (CBT) for GAD have demonstrated a degree of efficacy, but results have been disappointing when compared to CBT for other anxiety and mood disorders. Typically, only half of CBT-treated patients achieve high end-state functioning. More efficacious psychosocial treatments for GAD are clearly needed. Currently available treatments for GAD may have achieved less than satisfactory outcomes because they have not adequately targeted the essential difficulties that underlie GAD. That is, they have attempted to quell excessive worry and quiet somatic arousal but have not addressed these symptoms functionally. They have not asked, "Why does the person with GAD find worry an "appealing" strategy for managing emotional distress?" We take an emotional regulation approach to this question. Extensive preliminary research by our group on emotion dysregulation in GAD suggests that, while experiencing emotions as more intensely aversive than other people, persons with GAD are unable to identify, describe or accept their emotional experience, react maladaptively to both negative and positive emotions, and feel less able to repair negative moods when they occur. Furthermore, they demonstrate greater difficulties regulating experimentally induced negative emotions than persons without GAD. Worry may be a strategic effort to avoid feared and unmanageable emotional experience. Therefore, this exploratory research grant application will develop and manualize an approach to the treatment of GAD that integrates cognitive-behavioral procedures with techniques to increase patients' emotional regulation skills. The manual will be initially developed with the input of a panel of scientists expert in CBT, emotion-focused approaches to psychotherapy, psychotherapy integration, and emotion regulation and will be further developed in an open clinical trial and a small-scale randomized clinical trial. Data generated in this effort will serve as the basis for later grant applications to further evaluate the utility of this emotion regulation approach to treatment of GAD. Relevance: GAD is a common mental health problem associated with significant distress and impairment. However, current psychotherapeutic procedures have been less than optimally effective, and this may be because they have not focused on an important part of GAD, the inability to regulate one's emotional experience. This application will develop and test a manualized therapy that combines the best of current cognitive-behavioral procedures with techniques designed to help persons with GAD better regulate their emotional experience. The newly developed treatment will be evaluated in a series of small studies.

描述(申请人提供)：广泛性焦虑症(GAD)的特征是过度的、无法控制的焦虑和显著的中枢神经系统兴奋。它是普遍的，慢性的，并与显著的功能损害有关(现在被认为可与严重的抑郁障碍相媲美)。认知行为疗法(CBT)治疗广泛性焦虑症(GAD)已经显示出一定程度的疗效，但与其他焦虑和情绪障碍的CBT相比，结果令人失望。通常，接受CBT治疗的患者中只有一半实现了高端状态功能。显然需要对广泛性痴呆症进行更有效的心理社会治疗。目前对广泛性AD的现有治疗方法可能没有取得令人满意的结果，因为它们没有充分针对导致广泛性AD的根本困难。也就是说，他们试图平息过度的担忧和安静的躯体唤醒，但没有从功能上解决这些症状。他们还没有问，“为什么患有广泛性焦虑症的人会发现担忧是一种”有吸引力的“情绪困扰管理策略？”我们对这个问题采取了情绪调节的方法。我们小组对GAD情绪失调进行的广泛的初步研究表明，尽管GAD患者的情绪比其他人更令人厌恶，但他们无法识别、描述或接受自己的情绪体验，对负面和积极情绪都做出不适应的反应，当负面情绪发生时，感觉修复负面情绪的能力较差。此外，与没有GAD的人相比，他们表现出更大的困难来调节实验诱导的负面情绪。担忧可能是一种战略努力，以避免令人恐惧和无法管理的情绪体验。因此，这项探索性研究拨款申请将开发一种治疗广泛性AD的方法并将其具体化，将认知行为程序与提高患者情绪调节技能的技术相结合。该手册最初将在CBT、以情绪为重点的心理治疗方法、心理治疗整合和情绪调节方面的科学家专家小组的参与下开发，并将在开放临床试验和小规模随机临床试验中进一步开发。在这项工作中产生的数据将作为以后拨款申请的基础，以进一步评估这种情绪调节方法在治疗广泛性AD方面的效用。相关性：GAD是一种常见的精神健康问题，与严重的痛苦和损害有关。然而，目前的心理治疗程序并不是最有效的，这可能是因为它们没有关注GAD的一个重要部分，即无法调节一个人的情绪体验。该应用程序将开发和测试一种将当前最好的认知行为程序与旨在帮助GAD患者更好地调节他们的情绪体验的技术相结合的手动治疗方法。新开发的治疗方法将在一系列小型研究中进行评估。