Emotion Regulation Therapy for Generalized Anxiety

广泛性焦虑的情绪调节疗法

• 批准号: 7232027
• 负责人: RICHARD G HEIMBERG
• 金额: $ 20.41万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7232027
• 关键词: Address; American; Anger; Anxiety; Anxiety Disorders; Applications Grants; Arousal; Attention; Behavior Therapy; Behavioral; Biological Process; Blazer; Characteristics; Chronic; Clinical Trials; Cognition; Cognitive; Cognitive Therapy; Communities; Control Groups; DSM-III; DSM-IV; Daily; Data; Depressed mood; Development; Diagnosis; Diagnostic; Disease; Distress; Emotional; Emotions; Epidemiologic Studies; Evaluation; Event; Fright; Generalized Anxiety Disorder; Impairment; Individual; Informal Social Control; Intervention; Laboratories; Life; Major Depressive Disorder; Manuals; Measures; Mental Depression; Mental Health; Mental Processes; Modeling; Mood Disorders; Moods; Muscle Tension; Nature; Neuraxis; Outcome; Panic Disorder; Participant; Patient Self-Report; Patients; Pattern; Persons; Prevalence; Procedures; Psychotherapy; Quality of life; RNA Interference; Randomized Clinical Trials; Recurrence; Regulation; Relative (related person); Reliance; Reporting; Research; Research Personnel; Research Project Grants; Residual state; Robin bird; Role; Sampling; Scientist; Score; Series; Social Phobia; Social Work; Statistically Significant; Symptoms; Syndrome; Techniques; Testing; Thinking; affective neuroscience; base; clinically significant; cognitive control; design; disease classification; emotion regulation; emotional distress; emotional experience; experience; follow-up; functional disability; health care service utilization; improved; negative mood; novel; novel strategies; positive emotional state; programs; psychosocial; repaired; response; safran; skills; social; university student

DESCRIPTION (provided by applicant): Generalized Anxiety Disorder (GAD) is characterized by excessive, uncontrollable worry and significant central nervous system arousal. It is prevalent, chronic, and associated with significant functional impairment (now recognized as comparable to major depressive disorder). Cognitive-behavioral therapies (CBT) for GAD have demonstrated a degree of efficacy, but results have been disappointing when compared to CBT for other anxiety and mood disorders. Typically, only half of CBT-treated patients achieve high end-state functioning. More efficacious psychosocial treatments for GAD are clearly needed. Currently available treatments for GAD may have achieved less than satisfactory outcomes because they have not adequately targeted the essential difficulties that underlie GAD. That is, they have attempted to quell excessive worry and quiet somatic arousal but have not addressed these symptoms functionally. They have not asked, "Why does the person with GAD find worry an "appealing" strategy for managing emotional distress?" We take an emotional regulation approach to this question. Extensive preliminary research by our group on emotion dysregulation in GAD suggests that, while experiencing emotions as more intensely aversive than other people, persons with GAD are unable to identify, describe or accept their emotional experience, react maladaptively to both negative and positive emotions, and feel less able to repair negative moods when they occur. Furthermore, they demonstrate greater difficulties regulating experimentally induced negative emotions than persons without GAD. Worry may be a strategic effort to avoid feared and unmanageable emotional experience. Therefore, this exploratory research grant application will develop and manualize an approach to the treatment of GAD that integrates cognitive-behavioral procedures with techniques to increase patients' emotional regulation skills. The manual will be initially developed with the input of a panel of scientists expert in CBT, emotion-focused approaches to psychotherapy, psychotherapy integration, and emotion regulation and will be further developed in an open clinical trial and a small-scale randomized clinical trial. Data generated in this effort will serve as the basis for later grant applications to further evaluate the utility of this emotion regulation approach to treatment of GAD. Relevance: GAD is a common mental health problem associated with significant distress and impairment. However, current psychotherapeutic procedures have been less than optimally effective, and this may be because they have not focused on an important part of GAD, the inability to regulate one's emotional experience. This application will develop and test a manualized therapy that combines the best of current cognitive-behavioral procedures with techniques designed to help persons with GAD better regulate their emotional experience. The newly developed treatment will be evaluated in a series of small studies.

描述（由申请人提供）：广泛性焦虑症（GAD）的特征是过度的、无法控制的担忧和显著的中枢神经系统唤醒。它是一种流行的慢性疾病，并伴有明显的功能障碍（现在被认为与重度抑郁症相当）。GAD的认知行为疗法（CBT）已经证明了一定程度的疗效，但与其他焦虑和情绪障碍的CBT相比，结果令人失望。通常情况下，只有一半的CBT治疗的患者实现高终末状态功能。显然需要对广泛性焦虑症进行更有效的社会心理治疗。目前可用的GAD治疗可能取得了不太令人满意的结果，因为他们没有充分针对GAD的基本困难。也就是说，他们试图平息过度的担忧和安静的躯体唤醒，但没有从功能上解决这些症状。他们没有问：“为什么GAD患者会觉得担心是一种“有吸引力的”管理情绪困扰的策略？“我们对这个问题采取情绪调节的方法。我们小组对广泛性焦虑症患者的情绪失调进行了广泛的初步研究，研究表明，尽管他们的情绪比其他人更强烈地令人厌恶，但广泛性焦虑症患者无法识别、描述或接受他们的情绪体验，对消极情绪和积极情绪都做出不适应的反应，并且在消极情绪发生时，他们感到修复消极情绪的能力较低。此外，他们表现出更大的困难，调节实验诱导的负面情绪比没有广泛性焦虑症的人。担心可能是一种策略性的努力，以避免恐惧和无法控制的情绪体验。因此，这项探索性研究资助申请将开发和手动化一种治疗GAD的方法，该方法将认知行为程序与提高患者情绪调节技能的技术相结合。该手册最初将由CBT专家小组，以情绪为中心的心理治疗方法，心理治疗整合和情绪调节的科学家组成，并将在开放临床试验和小规模随机临床试验中进一步开发。在这项工作中产生的数据将作为基础，为以后的拨款申请，以进一步评估这种情绪调节方法治疗广泛性焦虑症的效用。相关性：广泛性焦虑症是一种常见的精神健康问题，与严重的痛苦和损害有关。然而，目前的心理治疗程序一直低于最佳效果，这可能是因为他们没有集中在广泛性焦虑症的一个重要组成部分，无法调节一个人的情绪体验。该应用程序将开发和测试一种手动治疗，该治疗将当前最好的认知行为程序与旨在帮助GAD患者更好地调节其情绪体验的技术相结合。新开发的治疗方法将在一系列小型研究中进行评估。