Bipolar Illness Intervention in Hispanic Communities

西班牙裔社区双相情感障碍干预

• 批准号: 7058753
• 负责人: CHARLES LEE BOWDEN
• 金额: $ 48.21万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-09 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7058753
• 关键词: Hispanic Americans; biomedical facility; bipolar depression; clinical research; community mental health services; health science research support; mental disorder prevention

DESCRIPTION (provided by applicant): This program seeks to establish a Developing Center for Interventions and Service Research (DCISR) that will forge an academic-community partnership to conduct interdisciplinary interventions research that will improve care of bipolar disorders, study moderators and mediators in the community that affect outcomes and participation in clinical research, and be of particular relevance to Hispanic Americans. The DCISR will enable the applicants to expand and develop their research capabilities, and contribute to greater alignment of research outcomes with community needs. With the DCISR infrastructure, the applicants will increase community involvement in study planning and management, and develop study designs better able to improve community-relevant interventions and the generalizability of results. These accomplishments will be greatly enriched by the opportunity to study in a comparative effort the Hispanic population that constitutes 55% of the population of the ninth largest city in the U.S. The DCISR brings together a multidisciplinary group of investigators with differing research foci around a central area of interventions and public health study on BD. The DCISR will develop a scale that provides an aggregate measure of psychopathology in BD, as well as sub-scale measurement of the full scope of depressive and manic symptomatology and will integrate data on clinical, treatment, neuroimaging, and genetic research in bipolar subjects into one central database. The training components of the Center will capitalize on the interdisciplinary model, with its potential for training beyond a primary focus of interest and access a broader group of mentors with relevant expertise to interventions research in BD. The scientific theme of the DCISR will be to provide a focal point for BD research in the UTHSCSA and the San Antonio area. Administration of the Center will be led by an Operations Committee that will have responsibility for the evaluation of intervention studies, linking research staff and objectives of the DCISR with the community and community stakeholders, oversight of data management and statistical operations, infrastructure development, training, program planning and insuring that the Center goals and vision are inculcated in all its activities. The committee will work to integrate the efforts of diverse faculty participating in the DCISR, meet with and solicit the input of the Community Advisory Committee, and convey the DCISR accomplishments within the Center and beyond. The OC will oversee maintenance of DCISR resources and relationships, and monitor all DCISR studies. The strategic plan of the Center emphasizes facilitating interdisciplinary investigation, forging alliances with the community, and incorporating the information learned from study of the community into modification of designs of intervention studies, recruitment efforts, and translational efforts back to community caregivers and patients with BD. These infrastructure developments will then support two developmental projects and additional pilot studies.

描述（由申请人提供）：该计划旨在建立一个发展中心的干预和服务研究中心（DCISR），该中心将建立一个学术社区的伙伴关系，以进行跨学科的干预研究，以改善对双相情感障碍的护理，研究社区中的调节剂和中介者，从而影响临床研究和参与临床研究以及特定相关的美国人，以及与他人有关的美国人和参与。 DCISR将使申请人能够扩展和发展其研究能力，并为更大的研究成果与社区需求保持一致。 借助DCISR基础架构，申请人将增加社区参与研究计划和管理，并开发研究设计能够更好地改善与社区相关的干预措施和结果的普遍性。 在比较努力中学习的机会将极大地丰富这些成就，这占美国第九大城市人口的55％，DCISR将围绕BD的干预措施和公共卫生研究的多学科研究人员组合在一起。 DCISR将开发一个量表，该量表可提供BD中心理病理学的综合度量，以及对抑郁症和躁狂症状的全部范围的亚尺度测量，并将在双极性受试者的临床，治疗，神经影像学和遗传研究中整合数据。 该中心的培训组成部分将利用跨学科模型，其潜力超出了感兴趣的主要重点，并获得了具有相关专业知识的更广泛的导师，以在BD中进行干预研究。 DCISR的科学主题是为UTHSCSA和圣安东尼奥地区的BD研究提供一个焦点。 该中心的管理将由运营委员会领导，该委员会将负责评估干预研究，将DCISR的研究人员和目标与社区和社区利益相关者联系起来，对数据管理和统计运营的监督，基础架构开发，培训，计划计划，并确保中心的所有活动灌输中心的目标和愿景。 该委员会将努力整合参加DCISR的各种教师的努力，与并征集社区咨询委员会的意见，并传达中心及以后的DCISR成就。 OC将监督DCISR资源和关系的维护，并监视所有DCISR研究。 该中心的战略计划强调促进跨学科的调查，与社区建立联盟，并将从对社区的研究中学到的信息纳入干预研究的设计，招聘工作的设计，以及转化努力，并向社区护理人员和BD患者进行翻译工作。 然后，这些基础设施发展将支持两个发展项目和其他试点研究。