Research Training Program in Pulmonary Host Defense, Inflammation and Immunity

肺宿主防御、炎症和免疫研究培训项目

• 批准号: 7067770
• 负责人: Claire M Doerschuk
• 金额: $ 12.83万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7067770
• 关键词: Research; Training; Program; Pulmonary; Host

DESCRIPTION (provided by applicant): This new application seeks funding for a multi-disciplinary research training program in Pulmonary Host Defense, Inflammation and Immunity at Case Western Reserve University School of Medicine and Health for pre-doctoral Ph.D. or M.D./Ph.D. students engaged in thesis work and for medical students engaged in shortterm research training. Presently, the research programs of Case faculty and the training programs for postdoctoral fellows and junior faculty in pulmonary host defense and in immunobiology are strong, and many pre-doctoral graduate and medical students are interested in joining these programs. There is a clear need for enlarging this pulmonary host defense community to include these students who are at earlier stages of their career, both to excite them about pursuing research careers in lung disease and to provide them outstanding training opportunities in inflammation and immunity. The objectives of this research training program are to 1) include these young students in this community, 2) provide outstanding multi-disciplinary research training and a rigorous background in pulmonary physiology in health and disease, 3) facilitate interactions that apply newly emerging information about basic mechanisms of inflammation and immunity to pulmonary disease, 4) develop new effective mentoring programs, and 5) provide an infrastructure. Our goals are to provide outstanding collaborative multidisciplinary research training to prepare our trainees for successful careers in pulmonary host defense and immunobiology, to train research and physician scientists to translate findings freely between the basic and clinical spheres, and to provide excellent mentor- and co-mentorship, which itself is taught to our trainees and evaluated by them. Short-term training for medical students will provide them an opportunity to pursue an area of research in greater depth than is accomplished within the traditional curriculum and increase awareness of opportunities in research through well structured, mentored research experiences that lay the foundation for future involvement in research. The outstanding, highly interactive 36 program faculty are based in 13 departments and have primary interests in four areas: lung immunobiology, tuberculosis, mechanisms of inflammation and innate immunity, or mucosal immunity. Thus, students will have opportunities through co-mentorship to learn about forefront advances in basic mechanisms in inflammation and immunity and to apply these to address important questions in lung biology. Underrepresented minorities are specifically recruited to join this program. Our evaluation system allows us to continuously improve our training program, and our database tracks the careers of these trainees. (End of Abstract)

描述（由申请人提供）： 这项新申请旨在为凯斯西储大学医学与健康学院的肺宿主防御，炎症和免疫多学科研究培训计划提供资金，以获得博士前博士学位。或医学博士/博士从事论文工作的学生和从事短期研究训练的医学生。目前，凯斯学院的研究项目以及博士后研究员和初级教师在肺宿主防御和免疫生物学方面的培训项目都很强大，许多博士前研究生和医学生都有兴趣加入这些项目。显然需要扩大这个肺部宿主防御社区，以包括这些处于职业生涯早期阶段的学生，既要激发他们从事肺部疾病的研究事业，又要为他们提供炎症和免疫方面的出色培训机会。该研究培训计划的目标是：1）将这些年轻学生纳入该社区，2）提供优秀的多学科研究培训和健康与疾病中肺生理学的严格背景，3）促进应用有关炎症和免疫基本机制的新信息的互动，4）开发新的有效指导计划，（5）提供基础设施。我们的目标是提供优秀的多学科合作研究培训，为我们的学员在肺宿主防御和免疫生物学方面的成功职业做好准备，培养研究和医生科学家在基础和临床领域之间自由翻译研究结果，并提供优秀的导师和共同导师，这本身就是教我们的学员并由他们评估。对医学生的短期培训将为他们提供一个机会，使他们能够比传统课程更深入地从事一个研究领域，并通过结构良好、有指导的研究经验，为未来参与研究奠定基础，提高对研究机会的认识。杰出的，高度互动的36个项目教师分布在13个部门，主要关注四个领域：肺免疫生物学，结核病，炎症和先天免疫机制或粘膜免疫。因此，学生将有机会通过共同导师学习炎症和免疫基本机制的前沿进展，并将其应用于解决肺部生物学中的重要问题。少数族裔被特别招募加入这一计划。我们的评估系统使我们能够不断改进我们的培训计划，我们的数据库跟踪这些学员的职业生涯。 (End摘要）