Cochlear Implant--Auditory Function & Speech Perception

项目描述（由申请人提供）：本项目的目标是研究电声联合刺激（EAS）患者的言语、声音和音乐感知能力，并将言语、声音和音乐感知与听觉领域潜在的心理生理能力联系起来。目标将通过与6个目标相关的实验和分析来实现。目的1是通过评估听觉阈值，获得耳蜗非线性加工、频率选择性和时间分辨率的估计，来表征植入前后残余听力患者的低频声学听力。目的2是评估单独的声刺激、单独的电刺激以及声电联合刺激对语音、声音和音乐识别测试的影响。目的3是确定低频声学听力的心理物理测量与语音、声音和音乐识别测量之间的关系。目的4是比较EAS患者、单侧种植体患者和双侧种植体患者在言语、声音和音乐识别方面的表现。目的5是评估相对于听觉区域的纯音，传递给电极的刺激的音高，并将电音高与耳蜗中电极位置的计算机x线摄影评估联系起来。目标6是进行滤波器频带到电极分配的研究，以评估(a)基于声学-电音高匹配（如目标5）将滤波器频带分配给电极是否比标准的滤波器频带分配产生更好的语音识别，以及(b)通过声学和电刺激表示低频的重叠是否对最大水平的性能是必要的。

DESCRIPTION (provided by applicant): The goal of this project is to conduct a study of the speech, voice and music perception abilities of patients who hear with combined electric and acoustic stimulation (EAS) and to relate speech, voice and music perception to underlying psychophysical abilities in the region of acoustic hearing. The goal will be met through experiments and analyses relative to 6 aims. Aim 1 is to characterize low frequency acoustic hearing in patients with residual hearing before and after implantation by assessing auditory thresholds and by obtaining estimates of nonlinear cochlear processing, frequency selectivity and temporal resolution. Aim 2 is to assess the effects of acoustic stimulation alone, electric stimulation alone and combined acoustic and electric stimulation on tests of speech, voice and music recognition. Aim 3 is to determine the relationships among the psychophysical measures of low-frequency acoustic hearing and the measures of speech, voice and music recognition. Aim 4 is to compare the performance of EAS patients, patients with unilateral implants and patients with bilateral implants on measures of speech, voice and music recognition. Aim 5 is to assess the pitch of stimulation delivered to electrodes relative to that of pure tones in the region of acoustic hearing and to relate electrical pitch to computerized radiography assessment of electrode position in the cochlea. Aim 6 is to conduct studies of filter-band-to-electrode assignments in order to assess (a) whether assigning filter-bands to electrodes based on acoustic-electric pitch matching (as in Aim 5) produces better speech recognition than a standard assignment of filter bands and (b) whether overlap in representation of low frequencies by acoustic and electric stimulation is necessary for maximum levels of performance.