Function and immunogenicity of the HIV-1 glycoproteins

HIV-1糖蛋白的功能和免疫原性

• 批准号: nhmrc : GNT1070890
• 负责人: A/Pr Heidi Drummer
• 金额: $ 41.05万
• 依托单位: Macfarlane Burnet Institute for Medical Research and Public Health Melbourne, Vic.
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/function-immunogenicity-hiv-1-glycoproteins/1344998
• 关键词: Function; immunogenicity; HIV; glycoproteins

More than 34 million people were living with HIV-1 in 2011 with ~7,000 new infections still occurring daily. A prophylactic vaccine for HIV-1 is needed to stop its transmission, however, this goal is yet to be achieved. Our proposed studies will inform the design of prophylactic HIV-1 vaccines that act by making antibodies that neutralize the virus.

2011年，超过3400万人感染了艾滋病毒-1，每天仍有约7,000例新感染病例。需要一种HIV-1的预防性疫苗来阻止其传播，然而，这一目标尚未实现。我们提出的研究将为预防性HIV-1疫苗的设计提供信息，这些疫苗通过制造中和病毒的抗体来发挥作用。