BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*

肉毒杆菌毒素治疗间质性膀胱炎/慢性*

• 批准号: 7259549
• 负责人: MARY P FITZGERALD
• 金额: $ 5.08万
• 依托单位: LOYOLA UNIVERSITY CHICAGO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2008-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7259549
• 关键词: botulinum toxins; chronic pain; clinical research; clinical trials; cooperative study; data management; human subject; human therapy evaluation; interdisciplinary collaboration; interstitial cystitis; medical outreach /case finding; patient oriented research; pelvis; questionnaires; sign /symptom; statistics /biometry; urinary tract disorder chemotherapy

DESCRIPTION (provided by applicant): The Loyola Female Pelvic Medicine team proposes to participate in the Interstitial Cystitis/Chronic Pelvic Pain (IC/CPP) Clinical Trials Network in order to advance the understanding of the clinical care of women with these complex disorders. Our multidisciplinary team has the clinical volume and proven ability to participate in development of cooperative studies and to recruit to finally approved protocols. As a referral center for IC/CPP in the Chicago area, we believe our participation will benefit the network by bringing a large patient base and a long clinical experience to the group, and will benefit our patients by making state-of-the-art treatments available to them. As requested in the RFA, we offer a concept protocol which studies the use of botulinum toxin injection into either detrusor or pelvic floor musculature, for the treatment of IC/CPP. The Loyola team: Understands the significance of this important treatment network, Can recruit and retain patients of racial, economic and ethnic diversity, Has experienced investigators including physicians, nurses, physical therapist and urodynamic technicians, Has a current clinical practice which offers surgical, pharmacological and behavioral treatment for IC/CPP, Can ensure data management and transmission, and Looks forward to cooperation with the other treatment centers in order to maximize the benefits of this treatment network for our patients.

描述(由申请人提供)： Loyola女性盆腔医疗队建议参加间质性膀胱炎/慢性盆腔疼痛(IC/CPP)临床试验网络，以促进对患有这些复杂疾病的妇女的临床护理的了解。我们的多学科团队有足够的临床数量和成熟的能力参与合作研究的开发，并招募到最终批准的方案。作为芝加哥地区IC/CPP的转诊中心，我们相信我们的参与将为集团带来庞大的患者基础和长期的临床经验，并将通过为患者提供最先进的治疗而使他们受益。 根据RFA的要求，我们提出了一个研究肉毒毒素注射到逼尿肌或盆底肌肉系统治疗IC/CPP的概念性方案。 洛约拉团队： 了解这一重要治疗网络的重要性， 可以招募和留住种族、经济和民族多样性的患者， 拥有经验丰富的调查人员，包括医生、护士、理疗师和尿流动力学技术人员， 目前的临床实践为IC/CPP提供手术、药物和行为治疗， 能够确保数据的管理和传输，以及 期待与其他治疗中心合作，以最大限度地发挥这一治疗网络为我们的患者带来的好处。