Latin American Cancer Research Coalition

描述（由申请人提供）： 据了解，美国约有3600万拉丁美洲人，到2050年，这一群体将占美国人口的25%。 癌症是这个迅速增长的少数群体的第二大死亡原因。 拉丁美洲人患传染性癌症的比率较高。 对于其他地区，尽管发病率较低，但与白人相比，拉丁美洲人有更多的晚期，更高的死亡率与发病率比，以及较差的生存率。 与文化适应相关的生活方式变化也可能增加未来的癌症风险。 大华盛顿-巴尔的摩三州地区（DC，马里兰州，弗吉尼亚州）是美国拉丁美洲人最大的城市集中地之一。该地区的拉丁美洲人主要是中美洲和南美洲血统，最近移民，无保险，主要是单语。 我们开发了拉丁美洲癌症研究联盟（LACRC），作为华盛顿特区的一个本地网络，以满足这一拉丁裔亚组的独特需求。 在我们的头4年，LACRC培训社区协调员，学生和教师，提交了R25 T博士后补助金，获得试点和职业发展资金，出版手稿，并与社区传播成果。 我们建议把该中心扩展为一个区域网络。 该区域网络的总体目标是记录，理解和减少拉丁美洲人的癌症差异。 LACRC的合作伙伴包括来自华盛顿医院中心/癌症研究所、伦巴第综合癌症中心、乔治敦大学、本地区19个社区安全网诊所、伊诺瓦-费尔法克斯社区医院的多学科、多文化和双语研究人员和工作人员，以及来自地区卫生和肿瘤登记处、拉丁美洲机构理事会、La Raza国家理事会、北美中央癌症登记协会、地区NCI癌症信息服务和西班牙语支持热线、ACS等。 法律咨询委员会的目标是：1）提高能力，特别是对拉丁美洲人的数据收集; 2）使用PRECEDE-PROCEED模型来指导参与性研究，并使用结果来通知教育，培训和规划;和3）获得资金，影响政策，并评估进展。 LACRC的结构非常适合作为一个平台，用于弥合研究发现和交付之间的差距，并在整个癌症控制领域开发，评估和传播文化上胜任的干预措施。 我们的方法应该广泛地适用于减少美国其他城市拉丁裔社区的差异

DESCRIPTION (provided by applicant): There are approximately 36 million Latinos known to be living in the US and by the year 2050, this group will constitute 25 percent of the US population. Cancer is the second leading cause of death among this rapidly growing minority group. Latinos have higher rates of cancers with infectious etiologies. For other sites, despite lower incidence, Latinos have more late stage, higher mortality-to-incidence ratios, and inferior survival compared to Caucasians. Lifestyle changes associated with acculturation may also increase future cancer risks. The greater Washington-Baltimore tri-state region (DC, Maryland, Virginia) has one of the largest urban concentrations of Latinos in the US. Latinos in this region are predominately of Central and South American ancestry, recently immigrated, un-insured, and largely monolingual. We developed the Latin American Cancer Research Coalition (LACRC) as a local network in DC to address the unique needs of this Latino subgroup. In our first 4 years, the LACRC trained community coordinators, students, and faculty, submitted an R25T post-doctoral grant, obtained pilot and career development funding, published manuscripts, and disseminated results with the community. We propose to expand the LACRC as a regional network. The overarching goal of this regional network is to document, understand, and reduce cancer disparities in Latinos. LACRC partners include multidisciplinary, multicultural, and bilingual researchers and staff from the Washington Hospital Center/Cancer Institute, Lombardi Comprehensive Cancer Center, Georgetown university, 19 community safety net clinics across our region, the Inova-Fairfax community hospital, and consultants and advisors from the regional Departments of Health and Tumor Registries, the Council of Latino Agencies, the National Council of La Raza, the North American Association of Central Cancer Registries, the regional NCI Cancer Information Service and Spanish-language support line, the ACS, and others. LACRC aims are to: 1) enhance capacity, especially for data collection on Latinos; 2) use the PRECEDE-PROCEED model to guide participatory research and use results to inform education, training, and planning; and 3) obtain funding, influence policy, and evaluate progress. The structure of the LACRC is ideally suited as a platform for bridging the gaps between research discovery and delivery, and developing, evaluating, and disseminating culturally competent interventions across the spectrum of cancer control. Our approach should be broadly portable to reducing disparities in other US urban Latino communities