Latin American Cancer Research Coalition

描述(由申请人提供)： 目前约有3600万拉丁裔居住在美国，到2050年，这一群体将占美国人口的25%。癌症是这一快速增长的少数群体中的第二大死因。拉美裔美国人患传染性癌症的几率更高。在其他地方，尽管发病率较低，但与高加索人相比，拉美裔人的晚期更多，死亡率/发病率更高，存活率更低。与文化适应相关的生活方式变化也可能增加未来的癌症风险。大华盛顿-巴尔的摩三州地区(华盛顿特区、马里兰州、弗吉尼亚州)拥有美国最大的拉美裔城市聚集地之一。这一地区的拉丁裔主要是中美洲和南美洲血统，最近移民，没有保险，主要是单一语言。我们建立了拉丁美洲癌症研究联盟(LACRC)，作为华盛顿特区的一个本地网络，以满足这一拉美裔亚群的独特需求。在我们最初的4年里，LACRC培训了社区协调员、学生和教职员工，提交了R25T博士后资助，获得了试点和职业发展资金，出版了手稿，并与社区一起传播了结果。我们建议将区域资源中心扩展为一个区域网络。这一区域网络的首要目标是记录、了解和减少拉美裔的癌症差异。LACRC的合作伙伴包括多学科、多文化和双语的研究人员和工作人员，他们来自华盛顿医院中心/癌症研究所、隆巴迪综合癌症中心、乔治敦大学、我们地区的19个社区安全网诊所、Inova-Fairfax社区医院，以及来自地区卫生和肿瘤登记部门、拉丁裔机构理事会、La Raza全国委员会、北美中央癌症登记协会、区域NCI癌症信息服务和西班牙语支持热线、ACS和其他部门的顾问和顾问。拉丁美洲和加勒比地区儿童权利倡议的目标是：1)提高能力，特别是收集关于拉美裔人的数据；2)利用先行模式指导参与性研究，并利用成果为教育、培训和规划提供信息；3)获得资金、影响政策和评估进展情况。LACRC的结构非常适合作为一个平台，用于弥合研究发现和交付之间的差距，并在癌症控制的各个领域开发、评估和传播具有文化能力的干预措施。我们的方法应该可以广泛移植到减少其他美国城市拉丁裔社区的差距

DESCRIPTION (provided by applicant): There are approximately 36 million Latinos known to be living in the US and by the year 2050, this group will constitute 25 percent of the US population. Cancer is the second leading cause of death among this rapidly growing minority group. Latinos have higher rates of cancers with infectious etiologies. For other sites, despite lower incidence, Latinos have more late stage, higher mortality-to-incidence ratios, and inferior survival compared to Caucasians. Lifestyle changes associated with acculturation may also increase future cancer risks. The greater Washington-Baltimore tri-state region (DC, Maryland, Virginia) has one of the largest urban concentrations of Latinos in the US. Latinos in this region are predominately of Central and South American ancestry, recently immigrated, un-insured, and largely monolingual. We developed the Latin American Cancer Research Coalition (LACRC) as a local network in DC to address the unique needs of this Latino subgroup. In our first 4 years, the LACRC trained community coordinators, students, and faculty, submitted an R25T post-doctoral grant, obtained pilot and career development funding, published manuscripts, and disseminated results with the community. We propose to expand the LACRC as a regional network. The overarching goal of this regional network is to document, understand, and reduce cancer disparities in Latinos. LACRC partners include multidisciplinary, multicultural, and bilingual researchers and staff from the Washington Hospital Center/Cancer Institute, Lombardi Comprehensive Cancer Center, Georgetown university, 19 community safety net clinics across our region, the Inova-Fairfax community hospital, and consultants and advisors from the regional Departments of Health and Tumor Registries, the Council of Latino Agencies, the National Council of La Raza, the North American Association of Central Cancer Registries, the regional NCI Cancer Information Service and Spanish-language support line, the ACS, and others. LACRC aims are to: 1) enhance capacity, especially for data collection on Latinos; 2) use the PRECEDE-PROCEED model to guide participatory research and use results to inform education, training, and planning; and 3) obtain funding, influence policy, and evaluate progress. The structure of the LACRC is ideally suited as a platform for bridging the gaps between research discovery and delivery, and developing, evaluating, and disseminating culturally competent interventions across the spectrum of cancer control. Our approach should be broadly portable to reducing disparities in other US urban Latino communities