Effects of Tibetan Yoga on Fatigue and Sleep in Cancer

藏式瑜伽对癌症疲劳和睡眠的影响

• 批准号: 7028155
• 负责人: Lorenzo Cohen
• 金额: $ 48.34万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-10 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7028155
• 关键词: China; alternative medicine; behavioral /social science research tag; breast neoplasms; clinical research; cognition; combination chemotherapy; emotional adjustment; fatigue; female; functional ability; human subject; meditation; neoplasm /cancer chemotherapy; physical fitness; psychological adaptation; psychological aspect of cancer; psychological stressor; quality of life; questionnaires; religion; respiratory function; sleep; social support network

DESCRIPTION (provided by applicant): Cancer and its treatment are associated with considerable distress, impaired quality of life, poor mental health, and reduced physical function. This is particularly true for women with breast cancer who receive multimodal treatment over an extended period of time. Many women undergo surgery and chemotherapy, which are often followed by radiotherapy. It is important to develop programs that can be incorporated into the treatment schedule that can help ameliorate the treatment-related morbidity that accumulates over time. Research suggests that stress-reduction programs tailored to the cancer treatment setting may help patients cope with the acute effects of treatment and improve their quality of life after treatment. Yoga, an ancient Eastern science, incorporates stress-reduction techniques including regulated breathing, visual imagery, and meditation, as well as various postures. Although different forms of yoga are practiced in many Eastern countries, most of what is known about yoga in the West comes from the Indian tradition. Less well know are the yogic practices from Tibet. For thousands of years, Tibetan's have been employing a form of yoga that incorporates controlled breathing and visualization, mindfulness techniques, and postures. We have designed and pilot-tested a Tibetan yoga program for cancer patients and found that it is feasible to conduct the intervention, and there is some initial indication that the intervention improves adjustment. We hypothesize that the yoga program we designed will be particularly useful for women with breast cancer who are undergoing adjuvant treatment for their disease as the focus is on controlled breathing, visualization, and mindfulness techniques, as well as some low impact gentle postures. The proposed study will assess the physical and psychological benefits of a Tibetan yoga program for women with breast cancer undergoing adjuvant chemotherapy. Patients with breast cancer who are scheduled to receive chemotherapy will be randomly assigned to either a Tibetan yoga group or an Educational Support group. This research will also evaluate the extent to which psychosocial factors mediate and/or moderate the intervention program and predict patients' recovery and adjustment to treatment. The effects of the intervention should be evident throughout recovery and across physical and psychological indices.

描述（由申请人提供）：癌症及其治疗与相当大的困扰，生活质量受损，精神健康不良和身体机能减少有关。对于长时间接受多模式治疗的乳腺癌女性而言，这尤其如此。许多妇女接受手术和化学疗法，通常进行放疗。重要的是要开发可以纳入治疗时间表中的程序，以帮助改善随着时间的推移积累的治疗相关的发病率。研究表明，减少针对癌症治疗设置的压力减少计划可以帮助患者应对治疗的急性影响并改善治疗后的生活质量。瑜伽是一门古老的东方科学，结合了减少压力的技术，包括受调节的呼吸，视觉图像和冥想以及各种姿势。尽管在许多东部国家都实践了不同形式的瑜伽，但西方瑜伽的大部分内容都来自印度的传统。西藏的瑜伽做法不太了解。数千年来，藏族一直在采用一种瑜伽形式，其中包含受控的呼吸和可视化，正念技巧和姿势。我们为癌症患者设计并试点测试了藏族瑜伽计划，并发现进行干预是可行的，并且有一些初始迹象表明干预措施改善了调整。我们假设我们设计的瑜伽计划对于正在接受辅助治疗的乳腺癌女性特别有用，因为重点是受控的呼吸，可视化和正念技术，以及一些低影响的柔和姿势。拟议的研究将评估藏族瑜伽计划对接受辅助化疗的乳腺癌女性的身体和心理益处。计划接受化疗的乳腺癌患者将随机分配给藏族瑜伽组或教育支持组。这项研究还将评估社会心理因素介导和/或缓和干预计划的程度，并预测患者的康复和适应治疗。干预的影响应在整个康复过程中以及整个身体和心理指数中显而易见。