Functional characterisation of the malaria protein export machinery

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The ability of malaria parasites to cause one of the most devastating infectious diseases of humans is in part due to their ability to export hundreds of proteins into their host red blood cells to obtain nutrients, evade the immune system and contribute to associated pathologies. Recently, we discovered the molecular machine that exports proteins into the host cell and so now we wish to establish how it works so that drugs can be tailored to block it to kill these parasites.