USF Scholars in Patient-Oriented Research (SPOR)

南佛罗里达大学以患者为导向的研究学者 (SPOR)

• 批准号: 7116445
• 负责人: Kenneth S. Zuckerman
• 金额: $ 30万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116445
• 关键词: USF; Scholars; Patient; Oriented; Research

DESCRIPTION (provided by applicant): This is a proposal is for a Scholars in Patient-Oriented Research (SPOR) Program at the University of South Florida (USF). USF has made major strides over the past decade toward the goal of becoming a major research university increasing external research funding from less than $25M to nearly $250M annually. Over half of this funding is in the Health Sciences Center (HSC). About half of this funding currently is from industry-sponsored clinical therapeutic trials, and with the other half of the funding is for investigator-initiated research. Thus, it is a priority of the USF HSC to concentrate on developing a strong cadre of faculty members with expertise in patient-oriented research that is capable of receiving peer-reviewed external funding, in addition, we have a clear need to upgrade the subspecialty fellowship training programs to train increasing numbers of subspecialty fellows to become academic clinical and translational researchers. The K30 grant is an ideal mechanism for jumpstarting these efforts. Fortunately, within our institution the Moffitt Cancer Center, an NCI-designated Comprehensive Cancer Center, has done an outstanding job of building a clinical research program, a clinical and translational research mentoring program for junior faculty, and a NCI K12- funded Clinical and Translational Research Training program. The proposed program will utilize the expertise developed at Moffitt, as well as many of the smaller foci of clinical research expertise at USF, to train junior faculty and fellows. The SPOR Program will lead to a Masters degree. It will consist of a core of classroom and web-based didactic teaching and a mentored clinical research project. Many of the courses already exist, and others will be derived from current courses, whereas some courses will be designed specifically for SPOR Program trainees. Required courses will include research and professional ethics; grantsmanship; scientific writing; diversity in clinical research; principles of cell biology, physiology, pharmacology, and molecular biology; biostatistics and informatics; fundamentals of successful patient-oriented research. There will be three tracks available: therapeutic clinical researchers (clinical trial design; Phase I/II clinical trial design, conduct, analysis and funding), population-based research (epidemiology and trial design), mechanisms of human disease (molecular basis of metabolism, clinical pharmacology, bioinformatics). A thesis or peer-reviewed publication(s) based on mentored research will be required. The executive committee will oversee the Program and will have subcommittees for (1) trainee selection, (2) mentor selection (3) curriculum (4) evaluation processes; and (5) overall SPOR Program progress. Process assessment will be based on evaluations of courses, mentored research, and the Program overall. The major long-term outcomes evaluated will include the number of trainees in academic positions, trainees doing productive clinical research (manuscripts and abstracts), and trainees with national peer-review funded clinical and translational research proqrams.

描述（由申请人提供）： 这是一个建议是在南佛罗里达大学（USF）的患者为导向的研究（SPOR）计划的学者。 USF在过去十年中朝着成为一所主要研究型大学的目标迈出了重大步伐，将外部研究资金从每年不到2500万美元增加到近2.5亿美元。 超过一半的资金用于健康科学中心（HSC）。 目前，大约一半的资金来自行业赞助的临床治疗试验，另一半资金用于制药商发起的研究。 因此，这是USF HSC的优先事项，集中精力发展一支强大的教师队伍，他们具有以患者为导向的研究方面的专业知识，能够接受同行评审的外部资金，此外，我们显然需要升级亚专业奖学金培训计划，以培训越来越多的亚专业研究员成为学术临床和转化研究人员。 K30赠款是启动这些努力的理想机制。 幸运的是，在我们的机构内，Moffitt癌症中心，一个NCI指定的综合癌症中心，在建立临床研究计划，为初级教师提供临床和转化研究指导计划以及NCI K12资助的临床和转化研究培训计划方面做得非常出色。 拟议的计划将利用莫菲特开发的专业知识，以及USF临床研究专业知识的许多较小的焦点，以培训初级教师和研究员。 SPOR计划将导致硕士学位。 它将包括一个核心的课堂和基于网络的教学和指导临床研究项目。 许多课程已经存在，其他课程将从现有课程中派生出来，而一些课程将专门为SPOR计划学员设计。 必修课程将包括研究和职业道德; granecraft;科学写作;临床研究的多样性;细胞生物学，生理学，药理学和分子生物学原理;生物统计学和信息学;成功的以患者为导向的研究的基础。 将有三个轨道可用：治疗临床研究人员（临床试验设计; I/II期临床试验设计，实施，分析和资助），基于人口的研究（流行病学和试验设计），人类疾病的机制（代谢的分子基础，临床药理学，生物信息学）。 论文或同行评审的出版物（S）的基础上指导的研究将是必需的。 执行委员会将监督该计划，并将设立小组委员会，负责（1）培训生选择，（2）导师选择，（3）课程设置，（4）评估流程，以及（5）SPOR计划的整体进展。 过程评估将基于对课程，指导研究和整个计划的评估。 评估的主要长期结果将包括学术职位的受训人员数量，进行生产性临床研究（手稿和摘要）的受训人员，以及国家同行评审资助的临床和转化研究项目的受训人员。