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Finite element modeling of Colles' fractures

Colles 骨折的有限元建模

基本信息

批准号：
6965076
负责人：
Karen L Troy
金额：
$ 4.88万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-12-01 至 2006-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6965076
关键词：
accidental falls biomechanics bone density chordate locomotion computer simulation disease /disorder proneness /risk frail elderly hand human subject injury prevention limb fracture mathematical model model design /development orthopedics physical model postdoctoral investigator wrist

项目摘要

DESCRIPTION (provided by applicant): Distal radius, or Colles' fractures, frequently occur in older adults after a fall. When wrist functionality is compromised, activities of daily living become difficult. Colles1 fractures are associated with complications such as secondary osteoarthritis and nonunions. Even in ideal situations substantial short- and long-term disability can result. Therefore, it is of interest to reduce the frequency with which these fractures occur. A finite element model of the wrist, incorporating relevant soft tissue and bone-density based material properties, is proposed. Experimentally derived boundary conditions including wrist flexion, ulna deviation, and all dynamic force components, will be applied to the model. Geometry and bone density information will be derived from high-resolution CT data. The effects of hand position and loading will be examined. Additionally, the effects of varying bone density will be explored. The aim of this work is to determine whether an optimal hand placement for exists that minimizes risk of fracture. A second aim of this work is to determine whether changes in bone density can lead to significantly decreased risk of fracture, and whether the level of density increase required is in a feasibly obtainable range for older adults.

描述(申请人提供)：桡骨远端骨折，或Colles‘s骨折，常发生在老年人跌倒后。当手腕功能受损时，日常生活活动就会变得困难。COLLES1骨折与继发性骨关节炎和骨不连等并发症有关。即使在理想情况下，也可能导致严重的短期和长期残疾。因此，降低这些骨折的发生频率是很有意义的。提出了一种腕关节的有限元模型，该模型包含了相关的软组织和基于骨密度的材料属性。实验得出的边界条件，包括手腕屈曲、尺骨偏差和所有动态力分量，都将应用于模型。几何和骨密度信息将从高分辨率CT数据中获得。将检查手部位置和负载的影响。此外，还将探讨不同骨密度的影响。这项工作的目的是确定是否存在将骨折风险降至最低的最佳手部位置。这项工作的第二个目的是确定骨密度的变化是否可以显著降低骨折的风险，以及所需的密度增加水平是否在老年人可行的范围内。