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Cognitive Processes, PTSD, and Alcohol Use

认知过程、创伤后应激障碍和饮酒

基本信息

批准号：
7004585
负责人：
DEBRA L KAYSEN
金额：
$ 2.59万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-01-01 至 2006-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7004585
关键词：
alcoholic beverage consumption alcoholism /alcohol abuse behavior prediction behavioral /social science research tag clinical research cognition comorbidity expectancy female human subject postdoctoral investigator posttraumatic stress disorder self medication sex abuse violence

项目摘要

DESCRIPTION (provided by applicant): Co-morbid PTSD and alcohol use disorders are both common and debilitating, therefore, identification of factors related to their development is of great import. Research findings support a self-medication hypothesis to explain this comorbidity. Yet mechanisms explaining the use of alcohol for self-medication of PTSD remain unaddressed. The overarching purpose of this study is to examine a cognitive model of AUD following traumatic events. This model will integrate cognitive processing theory of PTSD with models for the development of AUD emphasizing cognitive expectancies. This study will use a longitudinal design, assessing 100 adult women with a physical or sexual assault one, three, and six months after the traumatic event to determine how AUD develop over time, as a function of general and PTSD-specific alcohol outcome expectancies, cognitions affected by the traumatic event, and severity of PTSD symptoms. Aim 1: Examine general alcohol expectancies 1 month post-trauma, as predictors of alcohol consumption, and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 2: Examine PTSD severity I month post-trauma, as a predictor of alcohol consumption and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 3: Evaluate assimilation and over-accommodation I month post-trauma as predictors of PTSD symptoms 3 months post-trauma. Aim 4: Evaluate alcohol consumption, PTSD-specific alcohol expectancies, and PTSD severity 3 months post-trauma as predictors of alcohol use disorders 6 months post-trauma.

描述（由申请人提供）：共病的创伤后应激障碍和酒精使用障碍都是常见的和衰弱的，因此，识别与其发展相关的因素是非常重要的。研究结果支持自我药疗假说来解释这种合并症。然而，解释使用酒精进行创伤后应激障碍自我治疗的机制仍然没有得到解决。本研究的首要目的是检查创伤事件后AUD的认知模型。该模型将PTSD的认知加工理论与强调认知期望的AUD发展模型相结合。这项研究将采用纵向设计，评估100名成年女性在创伤事件发生后1个月、3个月和6个月遭受身体或性侵犯，以确定AUD如何随时间发展，作为一般和PTSD特异性酒精结果预期、受创伤事件影响的认知和PTSD症状严重程度的函数。目标1：检查创伤后1个月的一般酒精预期，作为酒精消费的预测因子，以及创伤后3个月的PTSD特异性酒精预期。目的2：检查创伤后1个月的PTSD严重程度，作为创伤后3个月饮酒和PTSD特异性酒精预期的预测因子。目的3：评估创伤后1个月同化和过度调节作为创伤后3个月PTSD症状的预测因子。目标4：评估创伤后3个月的饮酒量、创伤后应激障碍特异性酒精预期和创伤后应激障碍严重程度，作为创伤后6个月酒精使用障碍的预测因素。