Atomic Biomagnetometer

原子生物磁强计

• 批准号: 7123764
• 负责人: THAD G WALKER
• 金额: $ 17.15万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-22 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7123764
• 关键词: Atomic; Biomagnetometer

DESCRIPTION (provided by applicant): The long-term goal of this research program is to develop an optical magnetometer for use in fetal magnetocardiography (fMCG) and fetal magnetoencephalography {fMEG) systems. We believe that the proposed magnetometer, based on a major recent discovery,represents the first viable alternative to SQUID magnetometers; thus,the potential impact of the research on the field of biomagnetism is enormous. Utilization of fMCG and fMEG has been limited by the high cost of acquisition and maintenance associated with SQUID technology. The optical magnetometer can mitigate these disadvantages while n maintaining or even surpassing the magnetic field sensitivity of SQUID magnetometers. Thus far only the high sensitivity of the device has been demonstrated. The short-term goal of the research is to construct a device that is practical for human studies, while maintaining the high magnetic field sensitivity. The specific aims are: 1. To build a optical magnetometer/gradiometer that utilizes rubidium atoms and achieves a magnetic field sensitivity 10A-14 T/(Hz)A1/2. 2. To construct a miniaturized prototype magnetometer that would be practical for fetal n magnetocardiography. 3. To evaluate the performance of the magnetometer by assessing its signal and noise characteristics and by conducting phantom studies. 4. To justify classification of the magnetometer as a nonsignificant risk by assessing and eliminating n potential safety hazards.

描述（由申请人提供）： 该研究计划的长期目标是开发一种用于胎儿心磁图（fMCG）和胎儿脑磁图（fMEG）系统的光学磁力计。我们认为，拟议的磁力计，基于最近的一项重大发现，是SQUID磁力计的第一个可行的替代品;因此，生物磁学领域的研究的潜在影响是巨大的。fMCG和fMEG的利用受到与SQUID技术相关的高获取和维护成本的限制。光学磁强计可以在保持甚至超过SQUID磁强计的磁场灵敏度的同时减轻这些缺点。到目前为止，仅证明了该装置的高灵敏度。该研究的短期目标是构建一种适用于人类研究的设备，同时保持高磁场灵敏度。具体目标是：1.建立一个光学磁力计/梯度计，利用铷原子，并实现磁场灵敏度10 A-14 T/（Hz）A1/2。 2.建立一个小型化的原型磁力计，这将是实用的胎儿心磁图。3.通过评估磁力计的信号和噪声特性以及进行体模研究来评价磁力计的性能。4.通过评估和消除n个潜在安全危害，证明磁力计分类为非重大风险的合理性。