Duke Center for the Study of Public Genomics

杜克大学公共基因组学研究中心

• 批准号: 7112447
• 负责人: Robert Mullan Cook-Deegan
• 金额: $ 98.06万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7112447
• 关键词: biomedical facility; clinical research; functional /structural genomics; health related legal; information dissemination; molecular biology information system; nucleic acid sequence

DESCRIPTION (provided by applicant): Duke's Center for the Study of Public Genomics will gather and analyze information about the role of publication, data sharing, materials-sharing, patenting, database protection, and other practices that affect information flow in genomics research and development. Managing intellectual property and ensuring the preservation of a robust "scientific commons" could prove as difficult as or more so than the science and technology, and could have as large of an impact on what results are produced, who has access to them, and how fairly they are distributed. These are deeply ethical questions, highly dependent on policy decisions in government and the private sector. Intellectual property is new to the ELSI scene, but it is here to stay. The Center will combine qualitative and quantitative research and analysis involving Duke Arts & Sciences, the Medical School, Law School, Fuqua Business School, Sanford Institute for Public Policy, as well as the DNA Patent Database at Georgetown University. The Center builds on structures designed to enable collaborative research at Duke and with external organizations. The Center will bring together economists, legal scholars, molecular biologists, computational biologists, philosophers, English professors, and others. It will combine research training with Center research activity. The pervasiveness, importance, complexity, uncertainty, and persistence of concerns about the role of intellectual property will be addressed in four research projects, supported by four cores. The projects are: 1. case histories, including intellectual property landscapes of seminal genomic technologies and data sharing practices (DNA sequencing and microarray technologies, data-release and data-sharing practices); 2. models of open and collaborative production in genomics research and development; 3. intellectual property protection of databases and alternative regimes to reconcile public science with the commercialization of research results; and 4. empirical analysis of information flow in genomics based on a pilot survey.

描述(由申请人提供)：杜克公共基因组学研究中心将收集和分析有关发表、数据共享、材料共享、专利、数据库保护和其他影响基因组研究和开发中信息流的做法的作用的信息。管理知识产权和确保维护强大的“科学公地”可能被证明与科学和技术一样困难，甚至比科学和技术更困难，并可能对产生什么结果、谁有权获得这些成果以及这些成果的分配公平程度产生同样大的影响。这些都是根深蒂固的道德问题，高度依赖于政府和私营部门的决策。知识产权是ELSI领域的新事物，但它将继续存在。 该中心将结合定性和定量的研究和分析，涉及杜克大学艺术与科学学院、医学院、法学院、福库商学院、桑福德公共政策研究所以及乔治敦大学的DNA专利数据库。该中心建立在旨在促进杜克大学和外部组织合作研究的结构之上。该中心将汇集经济学家、法律学者、分子生物学家、计算生物学家、哲学家、英语教授和其他人。它将把研究培训与中心研究活动结合起来。 对知识产权作用的担忧的普遍性、重要性、复杂性、不确定性和持久性将在四个研究项目中得到解决，这些项目得到四个核心的支持。这些项目包括： 1.案例，包括种子基因组技术和数据共享做法(DNA测序和微阵列技术、数据发布和数据共享做法)的知识产权情况； 2.基因组研究与开发的开放协同生产模式； 3.保护数据库的知识产权和协调公共科学与研究成果商业化的替代制度；以及 4.基于试点调查的基因组信息流实证分析。