Advancing Child Health Through Cell & Molecular Biology

描述（由申请人提供）：密歇根大学儿童健康 研究职业发展奖（CHRCDA）计划，题为“促进儿童 健康通过细胞和分子生物学”的目的是支持 有前途的初级儿科教师的学术职业发展。 这 该计划特别强调儿科研究的三个领域- 发育生物学，异常细胞生长和宿主防御，从而采取 其他项目和研究人员的优势 在密歇根大学的各个角落。 具体而言，该计划旨在 支持初级儿科医生-科学家的研究培训， 细胞和分子生物学、生理基因组学和翻译 research. 该方案的具体目标是：（a）提供初级 儿科医生-科学家与功能基础设施技术 以确定疾病的潜在遗传和功能基础， 对儿童健康产生广泛影响;（B）提供一个独特的机会， 初级儿科医生科学家从相互作用中研究基因功能 在整个结构谱的核水平（核， （c）提供初级儿科 医生科学家有机会获得新的，创新的， 在分子和细胞领域拥有最先进的科学研究专长 生物学、生理基因组学和转化研究来弥补差距 基础科学研究与临床儿科医学之间的联系;（d） 初级儿科医生科学家的机会，发展专业知识， 使用表达分析核心的基因组和蛋白质组技术， 让他们接触到被认为是必要的教育核心课程， 追求成功的学术研究事业;及（e）吸引最多 有才华的初级儿科医生，科学家和招聘，发展和 培训少数民族和妇女成为独立调查员。 为了实现这一目标， 我们从不同的部门和单位招募了29名高级教师 整个部门。儿科医学院和霍华德休斯 医学研究所。

DESCRIPTION (provided by applicant): The University of Michigan Child Health Research Career Development Award (CHRCDA) program entitled "Advancing Child Health through Cellular and Molecular Biology" is designed to support the academic career development of promising junior pediatric faculty. This program places particular emphasis on three areas of pediatric research- developmental biology, abnormal cellular growth and host defenses, thus taking advantage of established strengths of other programs and investigators throughout the University of Michigan. Specifically, this program is designed to support research training of junior pediatric physician-scientists in cellular and molecular biology, physiologic genomics, and translational research. The specific goals of this program are: (a) to provide junior pediatric physician-scientists with the functional infrastructure technologies to determine the underlying genetic and functional basis of diseases that impact broadly on children's health; (b) to provide a unique opportunity for junior pediatric physician-scientists to study gene function from interactions at the nuclear level through the entire structural spectrum (nuclear, cellular, tissue, organ and organism); (c) to provide junior pediatric physician-scientists with an opportunity to acquire new, innovative and state-of-the-art scientific research expertise in molecular and cellular biology, physiologic genomics, and translational research to bridge the gap between basic science research and clinical pediatric medicine; (d) to give junior pediatric physician-scientists opportunities to develop expertise in both genomic and proteomic technology using the Expression Analysis Core and to expose them to an Educational Core Curriculum considered necessary for the pursuit of a successful academic research career; and(e) to attract the most talented junior pediatric physician-scientists and to recruit, develop and train minority and women as independent investigators. To achieve this aim, we have recruited 29 senior faculty members from diverse departments and units throughout the Dept. of Pediatrics, the Medical School, and the Howard Hughes Medical Institute.