Investigation of DPOAE components in time and frequency

DPOAE 成分的时间和频率研究

• 批准号: 6998475
• 负责人: Sumitrajit Dhar
• 金额: $ 6.95万
• 依托单位: NORTHWESTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6998475
• 关键词: auditory stimulus; clinical research; cochlea; hearing tests; human subject; otoacoustic emission

DESCRIPTION (provided by applicant): Otoacoustic emissions (OAEs) are signals generated in the cochlea, presumably as a byproduct of active physiological processes responsible for normal functioning of the ear. Distortion product OAEs (DPOAEs) are recorded by stimulating the cochlea simultaneously with two pure tones. A model in which DPOAEs recorded in the ear canal are represented as a composite signal comprised of contributions from several components has been proposed by Talmadge et al., (1998). Research recently has focused on the examination of specific properties of individual DPOAE components identified in this model. The goals of this study are to investigate the effect of input level on the main DPOAE components, and to examine the existence of multiple internal reflections in the cochlea as stimulus level is varied. Additionally, the data obtained during these experiments will allow the estimation of several model parameters. Overall, the results of these studies will improve our understanding of the DPOAE generative mechanisms and the basic mechanics of the cochlea. Such knowledge will invariably improve our ability to use DPOAEs as both a clinical and a research tool.

描述（由申请人提供）：耳声发射（OAE）是耳蜗中产生的信号，可能是负责耳朵正常功能的活跃生理过程的副产品。畸变产物耳声发射（DPOAE）是通过同时用两个纯音刺激耳蜗来记录的。Talmadge等人提出了一种模型，其中耳道中记录的DPOAE被表示为由来自若干分量的贡献组成的复合信号，（1998年）。最近的研究集中在检查在这个模型中确定的个别DPOAE组件的特定属性。本研究的目的是探讨输入强度对DPOAE主要成分的影响，并研究在不同的刺激强度下，耳蜗中是否存在多个内反射。此外，在这些实验中获得的数据将允许估计几个模型参数。总的来说，这些研究的结果将提高我们对DPOAE产生机制和耳蜗基本力学的理解。这些知识将不断提高我们使用DPOAE作为临床和研究工具的能力。

项目成果

DPOAE component estimates and their relationship to hearing thresholds.

DPOAE 分量估计值及其与听力阈值的关系。

• DOI: 10.3766/jaaa.17.4.6
• 发表时间: 2006
• 期刊: Journal of the American Academy of Audiology
• 影响因子: 1.2
• 作者: Shaffer,LaurenA;Dhar,Sumitrajit
• 通讯作者: Dhar,Sumitrajit