Mechanisms of cardiac longevity in the world's longest living vertebrate, The Greenland Shark

世界上寿命最长的脊椎动物格陵兰鲨的心脏长寿机制

• 批准号: 2775439
• 金额: --
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2775439
• 关键词: Mechanisms; cardiac; longevity; world; longest

Our project is strongly aligned to the BBSRC priority area of "Advancing the frontiers of bioscience discovery" by "Understanding the rules of life" which aims to "promote creative, curiosity-driven frontier bioscience to address fundamental questions in biology". In a world with rising life-expectancy, the mechanisms that drive longevity is perhaps one of the most fundamental questions of our time. In this project, we have the extraordinary opportunity to study the biology of the oldest known vertebrate and identify novel mechanisms that promote extreme longevity. The work is also aligned to the BBSRC priority area of "Tackling strategic challenges" as it directly addresses the "Bioscience for an integrated understanding of health" which aims to improve human health and wellbeing across the life course.

我们的项目与BBSRC的优先领域“推进生物科学发现的前沿”保持一致，“理解生命的规则”旨在“促进创造性，好奇心驱动的前沿生物科学，以解决生物学中的基本问题”。在一个预期寿命不断增长的世界里，推动长寿的机制可能是我们这个时代最根本的问题之一。在这个项目中，我们有非凡的机会来研究已知最古老的脊椎动物的生物学，并确定促进极端长寿的新机制。这项工作也与生物安全与健康研究中心的“应对战略挑战”优先领域保持一致，因为它直接涉及“生物科学促进对健康的综合理解”，旨在改善人类整个生命过程的健康和福祉。