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Mechanisms controlling liver development in zebrafish

Mechanisms controlling liver development in zebrafish
控制斑马鱼肝脏发育的机制
批准号：
7273476
负责人：
CHONG H SHIN
金额：
$5.2万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
项目状态：
已结题
起止时间：
2005-08-08 至 2008-08-07
来源：
https://reporter.nih.gov/project-details/7273476
关键词：
AdultAffectAmino AcidsAnimal ModelAntibodiesBile fluidBiological AssayBiological ModelsCell DeathCell ProliferationClassificationClinicalDefectDevelopmentEmbryoEmbryonic DevelopmentEndodermEventFellowshipGenesGeneticGenetic ScreeningGoalsGrowthHepatocyteHepatocyte Growth FactorIn VitroIndividualKnockout MiceLaboratoriesLearningLesionLiverMapsMesenchymeMessenger RNAMolecularNamesNatural regenerationOrganPathway interactionsPatternPhysiologicalProcessProductionProliferatingResearch ProposalsResearch TrainingRoleSignal PathwayStagingTherapeuticTissuesTubeVertebratesZebrafishbaseblood filtrationgain of functiongastrointestinal systemgene functionin vivoinsightmigrationmutantpositional cloningpreventreceptorsugartool

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中文摘要
翻译
描述（由申请人提供）：
英文摘要
DESCRIPTION (provided by applicant): Understanding the mechanisms involved in liver development is essential for answering how the liver acquires its physiological function. In addition, understanding the molecular events controlling the development of the embryonic as well as adult liver has the promise of providing a variety of therapeutic tools useful in clinical settings aimed at regulating liver growth and regeneration. This proposal aims at understanding the mechanisms controlling liver development using zebrafish as a model system.
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会议论文
Role of TBK1/IKK epsilon inhibition in pancreatic beta cell regeneration
  • 批准号：
    9539010
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2017
  • 负责人：
    CHONG H SHIN
  • 依托单位：
    GEORGIA INSTITUTE OF TECHNOLOGY
Mechanisms regulating hepatic specification and differentiation in zebrafish
  • 批准号：
    8258775
  • 项目类别：
  • 资助金额：
    $11.43万
  • 财政年份：
    2009
  • 负责人：
    CHONG H SHIN
  • 依托单位：
    GEORGIA INSTITUTE OF TECHNOLOGY
Mechanisms regulating hepatic specification and differentiation in zebrafish
Mechanisms regulating hepatic specification and differentiation in zebrafish
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