Expanding the range of barley gene editing tools

你想成为植物基因编辑（GE）专家并开发最新的气候适应作物吗？转基因或精确育种是一种显著的新工具，与现有的传统育种和转基因方法有着根本的不同。基因编辑直接精确地在优良作物品系的基因组内编辑目标基因，不需要额外的遗传物质，也不增加基因数量。更好地了解基因编辑工具对于支持谷物产量的生产至关重要，面对不断变化的气候，投入更少。这是一个为期4年的学生制，将允许您探索和开发尖端的GE方法，并有机会适应和开发自己的方法来创建新的编辑更改。大麦将发生变化，这与全球食品和饮料安全有关。GE通常用于诱导基因突变，从而敲除目标基因的功能，并产生相关的作物效益。你的学生的目的将是选择重要的基因靶点，开发不同的GE方法，并开发不同的方法将GE机器传递到植物细胞，使GE的潜力得到充分实现。我们已经建立了基因组和转录组数据集，这将有助于选择重要的基因靶点。在分子生物学方面有很强的背景会有所帮助，但我们在邓迪的詹姆斯赫顿研究所有人员和设施，可以让你发展自己的技能，并确定新的新基因靶点。

Do you want to become expert in plant gene editing (GE) and develop the newest range of climate ready crops? GE or precision breeding is a remarkable new tool that is fundamentally different from established conventional breeding and GM methods. Gene-editing edits the target gene directly and precisely within the genome of an elite crop line with no additional genetic material and no increase in gene number. A better understanding of gene editing tools is vitally important to support production of cereal yield, with fewer inputs in the face of a changing climate. This is a 4-year studentship that will allow you to explore and develop cutting-edge GE methods with the opportunity to adapt and develop your own methods of creating new edited changes. Changes will be made in barley that is relevant worldwide to food and drink security. GE is usually used to induce a gene mutation that knocks out the function of the targeted gene with the associated crop benefit. The aim of your studentship will be to select important gene targets, develop different GE methods and develop different methods of delivering the GE machinery to the plant cell allowing for the potential of GE to be fully realised. We have established genomic and transcriptomic datasets that will help select important gene targets. A strong background in molecular biology will help but we have people and facilities at the James Hutton Institute in Dundee that will allow you to develop your skills and identify new novel gene targets.