Expanding the range of barley gene editing tools

扩大大麦基因编辑工具的范围

• 批准号: 2869834
• 金额: --
• 依托单位: University of Dundee
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2869834
• 关键词: Expanding; range; barley; gene; editing

Do you want to become expert in plant gene editing (GE) and develop the newest range of climate ready crops? GE or precision breeding is a remarkable new tool that is fundamentally different from established conventional breeding and GM methods. Gene-editing edits the target gene directly and precisely within the genome of an elite crop line with no additional genetic material and no increase in gene number. A better understanding of gene editing tools is vitally important to support production of cereal yield, with fewer inputs in the face of a changing climate. This is a 4-year studentship that will allow you to explore and develop cutting-edge GE methods with the opportunity to adapt and develop your own methods of creating new edited changes. Changes will be made in barley that is relevant worldwide to food and drink security. GE is usually used to induce a gene mutation that knocks out the function of the targeted gene with the associated crop benefit. The aim of your studentship will be to select important gene targets, develop different GE methods and develop different methods of delivering the GE machinery to the plant cell allowing for the potential of GE to be fully realised. We have established genomic and transcriptomic datasets that will help select important gene targets. A strong background in molecular biology will help but we have people and facilities at the James Hutton Institute in Dundee that will allow you to develop your skills and identify new novel gene targets.

您想成为植物基因编辑 (GE) 专家并开发最新系列的气候适应作物吗？ GE 或精准育种是一种非凡的新工具，与现有的传统育种和转基因方法根本不同。基因编辑直接、精确地在优良作物品系的基因组内编辑目标基因，无需额外的遗传物质，也不会增加基因数量。更好地了解基因编辑工具对于支持谷物产量至关重要，在气候变化的情况下减少投入。这是一个为期 4 年的学生项目，让您能够探索和开发尖端的 GE 方法，并有机会适应和开发自己的方法来创建新的编辑更改。大麦将发生与全球食品和饮料安全相关的变化。转基因通常用于诱导基因突变，从而消除目标基因的功能以及相关的作物效益。您的学生奖学金的目的将是选择重要的基因靶标，开发不同的基因工程方法，并开发将基因工程机械传递到植物细胞的不同方法，从而充分发挥基因工程的潜力。我们已经建立了基因组和转录组数据集，这将有助于选择重要的基因靶标。强大的分子生物学背景会有所帮助，但我们在邓迪的詹姆斯赫顿研究所拥有人员和设施，可以让您发展您的技能并识别新的基因靶点。