Nebraska Redox Biology Center

内布拉斯加州氧化还原生物中心

• 批准号: 6912824
• 负责人: RUMA V BANERJEE
• 金额: $ 212.04万
• 依托单位: UNIVERSITY OF NEBRASKA LINCOLN
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6912824
• 关键词: cooperative study; health science research support; interdisciplinary collaboration; oxidation reduction reaction

DESCRIPTION (provided by applicant): This IDeA proposal presents a detailed plan to create a rnultidisciplinary Center for Biomedical Research Excellence (COBRE) in Nebraska for Redox Biology. The Center will link scientists at the two leading research-active institutions in the state - the UN-Lincoln and the UNMC - in a collaborative pursuit to unravel fundamental problems in redox biology that impact the pathogenesis of a number of diseases including some cancers, arthritis and cardiovascular diseases and the progression of natural phenomena such as aging. The objectives of the proposed Center are (i) to enhance biomedical research capacity in the state by creating an infrastructure that will strategically link strong research programs in redox biology at the two institutions and (ii) to mentor a cadre of junior faculty to independent funding success at NIH. These objectives will be met by providing a rich and rigorous mentoring environment for junior investigators, by bolstering core facilities, by fostering collaborations among scientists at both institutions and by recruiting five additional faculty members with research interests in the area of redox biology to ensure the critical mass of scientists necessary to sustain a nationally visible and internationally recognized Center. A key design feature for the organization of the Center is the mentoring of each of the five developing faculty members by an established investigator with similar research interests and a successful track record of funding at NIH. As these project leaders transition to funding independence, their projects will be replaced by ones led by the newly recruited faculty members. A Director with the vision, scientific expertise and administrative experience necessary to provide effective leadership will be primarily responsible for steering the Center. She will be counseled by members of the Mentoring Council, comprising five established scientists at the Nebraska institutions, and guided by an External Advisory Council (EAC) comprising eight outstanding scientists, five of whom are members of the National Academy of Sciences, and all of whom have agreed to serve in this capacity. The synergistic environment resulting from the creation of the Center will enrich the culture of research in the state, will enliven its community of biomedical scientists and will elevate the quality and offerings of key core facilities.

描述（由申请人提供）：这个IDeA提案提出了一个详细的计划，在内布拉斯加州为氧化还原生物学创建一个跨学科的生物医学研究卓越中心（COBRE）。该中心将把该州两家领先的研究活跃机构——联合国-林肯中心和UNMC中心的科学家联系起来，共同探索氧化还原生物学的基本问题，这些问题影响许多疾病的发病机制，包括一些癌症、关节炎和心血管疾病，以及衰老等自然现象的进展。该中心的目标是：(1)通过建立一个基础设施，将两个机构在氧化还原生物学方面的强大研究项目战略性地联系起来，从而提高该州的生物医学研究能力；(2)指导一群初级教师在NIH获得独立资助。