Learning how DNA and proteins interact through experiments and AI

通过实验和人工智能了解 DNA 和蛋白质如何相互作用

• 批准号: 2871262
• 金额: --
• 依托单位: University of Edinburgh
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2871262
• 关键词: Learning; how; DNA; proteins; interact

Proteins and DNA are responsible for most functions and dysfunction in living organisms. There is great interest in understanding how DNA is regulated by proteins and when dysfunction of these proteins leads to disease. To gain a better understanding of how certain proteins bind and manipulate DNA, we will use a combination of soft matter experimental methods and machine learning approaches to study this in detail.

蛋白质和DNA负责生物体中的大多数功能和功能障碍。人们对了解DNA如何受蛋白质调节以及这些蛋白质的功能障碍何时导致疾病有很大的兴趣。为了更好地了解某些蛋白质如何结合和操纵DNA，我们将结合软物质实验方法和机器学习方法来详细研究。