CORE--DATA MANAGEMENT AND BIOSTATISTICS

核心——数据管理和生物统计学

• 批准号: 6932657
• 负责人: ELLEN M WIJSMAN
• 金额: $ 20.46万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6932657
• 关键词: Alzheimer' s disease; biomedical facility; computational biology; data management; experimental designs; genetics; statistics /biometry

The primary objective of this Core is to provide data management, statistical genetic, and biostatistical support to the Cores and Projects of the University of Washington Alzheimer's Disease Research Center (ADRC). Our specific aims are: (1) To provide database management support to projects, cores and pilot projects;(2) To provide support to projects, cores and pilot projects in the areas of statistical and statistical genetic design and analysis at the UW ADRC and at other ADCs; (3) To assist projects, cores, and pilot projects in manuscript preparation relating to statistical and statistical genetic analyses; (4) To maintain a proactive approach to provision of such support; and (5) To evaluate, develop, extend, and apply appropriate statistical and statistical genetic methodologies for problems arising out of projects, cores, and pilot projects. Core computer specialists construct, modify, and maintain the databases needed to store and access the ADRC data for the analytical needs of the cores and projects, and to be able to extract data for submission to the National Alzheimer's Disease Coordinating Center. Core computer specialists also maintain the computer hardware and the systems level software needed for access to the analysis computers and to the databases via the internet, while at the same time keeping the computer systems up-to-date in terms of security, to prevent unauthorized access. Core computer specialists and research consultants are also available to provide some programming services, as needed, to all cores and projects. Core statistical geneticists and biostatisticians are available to all cores and projects for consultation and assistance regarding design, analysis, and interpretation of data, and preparation of manuscripts using such approaches. This includes evaluation, extension, and development of new analytical methodology and the authoring and coauthoring of manuscripts based on such new methods.

该核心的主要目标是为华盛顿大学阿尔茨海默病研究中心（ADRC）的核心和项目提供数据管理、统计遗传学和生物统计学支持。我们的具体目标是：(1)为项目、核心和试点项目提供数据库管理支持；(2)为西澳大学抗菌素研究中心和其他抗菌素研究中心的统计和统计遗传设计与分析领域的项目、核心项目和试点项目提供支持；(3)协助统计和统计遗传分析相关的项目、核心和试点项目的稿件编写；(4)在提供这种支助方面保持积极主动的态度；(5)评估、发展、扩展和应用适当的统计