Data Management & Statistics Core

核心C：DMS-摘要 数据管理和统计核心的主要目标是提供数据管理和 对华盛顿大学阿尔茨海默病研究核心和项目的统计支持 中心(UW ADRC)。数据核心计算机和数据管理专家构建、修改和 维护存储和访问核心和项目的UW ADRC数据所需的数据库，同时 确保最新的计算机安全。他们协调所有数据流、数据更正和数据录入；执行 数据质量控制和质量保证分析；并将数据提交给国家阿尔茨海默病 与其他调查人员共享的协调中心。数据管理和统计核心统计师是 向所有核心、项目和试点项目提供关于统计设计的咨询和协助， 分析和解释数据，以及编写使用这种方法的手稿 在软件中开发和/或实施新的分析方法。 具体目标是：(1)为项目、核心和试点项目提供数据库管理支持。 这将包括所有临床核心数据的数据库条目；及时上传临床、神经病理学和有针对性的数据 向NACC提供基因分型数据；跟踪和监测数据收集、完成和质量；协调 核心之间的数据流动；协调和处理数据校正；协助数据提取； 以及数据库的维护和持续开发。(二)为项目提供统计支持， 核心、试点项目和ADRC资源的其他用户。这将包括提供以下方面的统计咨询 设计、分析和解释结果；进行数据分析；协助相关手稿 筹备；评估和推广亚洲发展研究中心项目产生的问题的统计方法。(3) 维护实现目标1和目标2所需的计算环境。 UW ADRC的数据管理和统计核心将提供必要的数据管理 高效、准确地存储中心收集的数据所需的协助。它还将促进 将数据转化为与阿尔茨海默氏症的预防、治疗或诊断有关的科学发现 通过协助进行统计数据分析来预防和控制疾病。在此过程中，数据核心成员的活动 朝向这些目标将有助于UW ADRC在其使命中减轻负担的总体目标 阿尔茨海默氏症。

CORE C: DMS - ABSTRACT The primary objective of the Data Management and Statistics Core is to provide data management and statistical support to the Cores and Projects of the University of Washington Alzheimer's Disease Research Center (UW ADRC). The Data Core computer and data management specialists construct, modify, and maintain the databases needed to store and access the UW ADRC data for the cores and projects, while ensuring up-to-date computer security. They coordinate all data flow, data corrections and data entry; carry out data quality control and quality assurance analyses; and submit data to the National Alzheimer's disease Coordinating Center for sharing with other investigators. Data Management and Statistics Core statisticians are available to all Cores, Projects, and Pilot Projects for consultation and assistance regarding statistical design, analysis, and interpretation of data, as well as preparation of manuscripts that use such approaches and developing and/or implementing in software new analytical methodology. The specific aims are: (1) To provide database management support for projects, cores and pilot projects. This will include database entry of all Clinical Core data; timely upload of clinical, neuropathology, and targeted genotyping data to NACC; tracking and monitoring of data collection, completion and quality; coordination of data flow between the cores; coordinating and processing of data corrections; assisting with data extractions; and maintenance and continued development of the databases. (2) To provide statistical support for projects, cores, pilot projects and other users of ADRC resources. This will include providing statistical consultation on design, analysis, and interpretation of results; carrying out data analyses; assisting with associated manuscript preparation; evaluating and extending statistical methodologies for problems arising out of ADRC projects. (3) To maintain the computing environment needed to achieve aims 1 and 2. The Data Management and Statistics Core of the UW ADRC will provide the necessary data management assistance needed to efficiently and accurately store the data collected by the center. It will also facilitate the translation of data to scientific discoveries relevant to the prevention, treatement or diagnosis of Alzheimer's disease through assistance with statistical data analysis. In doing so, the activities of Data Core members towards these goals will facilitate the overall goals of the UW ADRC in its mission toward reducing the burden of Alzheimer's disease.