Comprehensive MMC/VICC Cancer Research Partnership

描述(由申请人提供) 众所周知，少数群体患癌症的比例不成比例。 死亡率和发病率均存在差异。其他 公认的问题是少数民族科学家和医生的匮乏 从事癌症研究和不成比例的少数族裔 进入临床试验。梅哈里医学院(MMC)有一所 培养了一大部分非裔美国人的杰出历史 目前活跃在美国的医生。而MMC长期以来一直 积极参与癌症研究，这些活动的承诺还没有实现 果子。范德比尔特-英格拉姆癌症中心(VICC)是NCI指定的研究密集型中心 癌症中心具有非常强的基础性、转化性、临床性、 预防和以人口为基础的研究方案。MMC和VICC位于 在纳什维尔内相距约两英里。有很长的历史 两个机构之间的教员互动，以及最近的 Meharry-Vanderbilt联盟的建立为 为快速发展MSI/CC伙伴关系提供支持的基础设施 摘自CCSG附录。此U54应用程序的总体目标是 加强和扩大两国之间现有的癌症研究伙伴关系 MMC和VICC要达到三个目的：(1)增加和稳定 MMC具有竞争力的癌症研究能力；(2)创造稳定、长期的 MMC和VICC在癌症研究中的合作关系， 研究培训和职业发展；以及，(3)改善 MMC和VICC在开展侧重于 年少数民族人群的发病率、死亡率和发病率不成比例 中南部。我们为实现这些目标而设计的计划是有指导意义的 为每个机构的管理和规划提供适度的核心 评估。该项目的研究活动载于 由基础科学、癌症等组成部分组成的发展核心 预防、结果和外展，以及临床调查。我们建议 为六个试点项目和四个共享资源提供资金。两个基本要素 科学家，一名内科肿瘤学家，一名外科肿瘤学家和两名 流行病学家，将被招募加入MMC教职员工与联合 在这笔赠款的赞助下任命范德比尔特。我们建议 MMC教师通过正规培训计划和 培训少数民族肿瘤内科医生、少数民族研究护士和数据 管理人员、少数族裔博士生和MMC医学生基础和 临床癌症研究。

DESCRIPTION (provided by applicant) It is well known that minority groups suffer disproportionately from cancers with disparities existing in both the mortality and incidence rates. Other well-recognized problems are the paucity of minority scientists and physicians working in cancer research and the disproportionate number of minorities being entered into clinical trials. Meharry Medical College (MMC) has a distinguished history of training a large percentage of the African American physicians currently active in the United States. While MMC has long been active in cancer research, the promise of these activities has not yet reached fruition. Vanderbilt-Ingram Cancer Center (VICC) is a research intensive NCI-designated cancer center with very strong basic, translational, clinical, prevention and population-based research programs. MMC and VICC are located approximately two miles apart within Nashville. There has been a long history of faculty interactions between the two institutions, and the more recent establishment of the Meharry-Vanderbilt Alliance has provided the infrastructure for the rapid development of a MSI/CC partnership with support from the CCSG supplement. The overall objectives of this U54 application are to strengthen and expand the existing partnership for cancer research between MMC and the VICC to achieve three ends: (1) to increase and stabilize the competitive cancer research capability of MMC; (2) to create stable, long term collaborative relationships between MMC and the VICC in cancer research, research training and career development; and, (3) to improve the effectiveness of MMC and the VICC in conducting activities focused on the disproportionate incidence, mortality and morbidity in minority populations in the mid-south. The programs we have designed to achieve these ends are guided by modest cores for administration at each institution and for planning and evaluation. Research activities for the project are contained in a development core that consists of components in basic science, cancer prevention, outcomes and outreach, and clinical investigations. We propose funding of six pilot projects and four shared resources. Two basic scientists, one medical oncologist one surgical oncologists and two epidemiologists, will be recruited to join the MMC faculty with joint appointments at Vanderbilt under the auspices of this grant. We propose career development of MMC faculty through formal training programs and training of a minority medical oncologist, minority research nurses and data managers, minority Ph.D. candidates, and MMC medical students in basic and clinical cancer research.