2nd International Pathogenesis of Rare Neuroimmunologic Disorders

第二届国际罕见神经免疫性疾病发病机制

基本信息

  • 批准号:
    7162413
  • 负责人:
  • 金额:
    $ 1.5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2006
  • 资助国家:
    美国
  • 起止时间:
    2006-07-01 至 2007-06-30
  • 项目状态:
    已结题

项目摘要

Neuroimmunologic disorders are a loosely defined group of disorders in which there is an immunemediated injury of the nervous system that include the following: polymyositis, myasthenia gravis (MG), inflammatory polyneuropathies, transverse myelitis, HTLV-1 associated myelopathy, stiff person syndrome (SPS), neuromyelitis optica (NMO), optic neuritis (ON), multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), Hashimoto?s encephalitis, Rasmussen?s encephalitis, paraneoplastic encephalomyelitis (PE), and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS). Also included in this list are neurologic manifestations of sarcoidosis, Sjogren?s syndrome, infections (i.e. JC virus, meningitis and HIV) and responses of manipulating the immune system (immune reconstitution syndrome). Though each disorder is unique, there are shared immunopathogenic mechanisms among many of them that justify their study as entities on a single spectrum. To further explore this and to continue the collaborations forged at a similar symposium in 2004, we have organized the 2 2nd nd international ?Pathogenesis of Rare Neuroimmunologic Disorders? workshop to be held at the Sheraton in Baltimore MD from July 20th-22nd, 2006. The workshop will not be disease oriented, but rather, mechanism oriented, and will involve discussions of many neuroimmunologic disorders as they pertain to mechanisms of autoimmunity in the nervous system. This workshop will focus on rare neuroimmunologic disorders, rather than on the most common disease in this group, MS. However, participants will be invited to discuss advances in MS specifically as these advances inform and educate research in other neuroimmunologic disorders. Participants will explore the following common themes: Genetics and triggering mechanisms; humoral contributions to autoimmunity; cellular contributions to autoimmunity, migration of immune cells; innate immune contributions; neuroprotection; neural-immune cross talk; remyelination; novel imaging and emerging immunotherapies. Participants will learn where the disorders are similar and therefore benefit from similar therapeutic approaches; and where they are distinct, elucidating the need for unique treatment strategies. The central premise of the symposium is that by discussing unique and shared pathologic processes of a group of rare disorders, participants will stimulate novel, collaborative investigations necessary to advance understanding of these disorders. The workshop will be small and interactive, distinguishing it from other larger symposia which typically emphasize the more common neuroimmunologic disorders (especially multiple sclerosis) and are largely didactic. The workshop will solicit participation from both senior and junior scientists/students in order to stimulate long-term research in these disorders. The proceedings will be disseminated in the medical literature.
神经免疫性疾病是一组定义松散的疾病,其中有免疫介导

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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DOUGLAS A KERR其他文献

DOUGLAS A KERR的其他文献

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{{ truncateString('DOUGLAS A KERR', 18)}}的其他基金

Stem Cell-Derived Motoneurons in the Adult mammalian CNS
成年哺乳动物中枢神经系统中干细胞衍生的运动神经元
  • 批准号:
    7216197
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
ES Cell-Derived Motoneurons from SMA transgenic mice
来自 SMA 转基因小鼠的 ES 细胞衍生的运动神经元
  • 批准号:
    7368089
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
ES Cell-Derived Motoneurons from SMA transgenic mice
来自 SMA 转基因小鼠的 ES 细胞衍生的运动神经元
  • 批准号:
    7210762
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
ES Cell-Derived Motoneurons from SMA transgenic mice
来自 SMA 转基因小鼠的 ES 细胞衍生的运动神经元
  • 批准号:
    6873080
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
Stem Cell-Derived Motoneurons in the Adult mammalian CNS
成年哺乳动物中枢神经系统中干细胞衍生的运动神经元
  • 批准号:
    7013966
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
Stem Cell-Derived Motoneurons in the Adult mammalian CNS
成年哺乳动物中枢神经系统中干细胞衍生的运动神经元
  • 批准号:
    7407424
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
ES Cell-Derived Motoneurons from SMA transgenic mice
来自 SMA 转基因小鼠的 ES 细胞衍生的运动神经元
  • 批准号:
    7017702
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
Stem Cell-Derived Motoneurons in the Adult Mammalian CNS
成年哺乳动物中枢神经系统中干细胞衍生的运动神经元
  • 批准号:
    6855000
  • 财政年份:
    2005
  • 资助金额:
    $ 1.5万
  • 项目类别:
Pathogenesis of Rare Neuroimmunologic Disorders
罕见神经免疫疾病的发病机制
  • 批准号:
    6837512
  • 财政年份:
    2004
  • 资助金额:
    $ 1.5万
  • 项目类别:
INVESTIGATION OF THE ROLE OF SMN IN NEURONAL APOPTOSIS
SMN 在神经元凋亡中的作用研究
  • 批准号:
    6024691
  • 财政年份:
    1999
  • 资助金额:
    $ 1.5万
  • 项目类别:
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