HIV-1 Solid Phase Proteoliposome
HIV-1 Solid Phase Proteoliposome
批准号:
7184256
负责人:
Richard Thomas Wyatt
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
HIV envelope protein gp120SDS polyacrylamide gel electrophoresisaffinity chromatographycytokine receptorsflow cytometryglycoprotein structurehuman immunodeficiency virus 1lipid bilayer membranemolecular biologyneutralizing antibodypeptide chemical synthesispolymerase chain reactionprotein reconstitutionprotein structureproteolipidsrecombinant DNAtransfectionvirus receptors
中文摘要
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英文摘要
Monomeric HIV-1 gp120 exterior envelope glycoproteins have failed to efficiently elicit neutralizing antibodies. We have therefore attempted to reconstitute the trimeric native g120 structure as solid phase proteoliposomes (PLs) containing HIV envelope glycoproteins (EnvPLs). This study characterizes the native trimeric structure of the glycoproteins in a lipid bilayer environment.
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Core-002
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批准号:10794904
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项目类别:
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资助金额:$113.05万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates
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批准号:10339439
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项目类别:
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资助金额:$342.0万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Project 1
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批准号:10339443
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项目类别:
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资助金额:$115.59万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Admin Core
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批准号:10339440
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项目类别:
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资助金额:$21.4万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Core-001
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批准号:10782243
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项目类别:
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资助金额:$139.64万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Project-002
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批准号:10794919
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项目类别:
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资助金额:$50.33万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Eliciting neutralizing antibodies and B cell responses using novel HIV Env immunogens in non-human primates
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批准号:10549838
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项目类别:
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资助金额:$340.27万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
Admin-Core-001
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批准号:10794918
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项目类别:
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资助金额:$37.25万
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财政年份:2021
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负责人:Richard Thomas Wyatt
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依托单位:
N-glycan baiting to target the highly effective HIV Env shield
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批准号:10388295
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项目类别:
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资助金额:$96.18万
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财政年份:2019
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负责人:Richard Thomas Wyatt
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依托单位:
N-glycan baiting to target the highly effective HIV Env shield
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批准号:9754560
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项目类别:
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资助金额:$67.15万
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财政年份:2019
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负责人:Richard Thomas Wyatt
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依托单位:
N-glycan baiting to target the highly effective HIV Env shield
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批准号:10333202
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项目类别:
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资助金额:$96.18万
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财政年份:2019
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负责人:Richard Thomas Wyatt
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依托单位:
N-glycan baiting to target the highly effective HIV Env shield
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批准号:9918868
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项目类别:
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资助金额:$67.15万
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财政年份:2019
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负责人:Richard Thomas Wyatt
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依托单位:
High Resolution Analysis of Env-directed B Cells to Accelerate Vaccine Design
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批准号:8680621
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项目类别:
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资助金额:$265.98万
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财政年份:2014
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负责人:Richard Thomas Wyatt
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依托单位:
Structure and Immunogenicity of HIV-1 gp41 Membrane Prox
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批准号:7299877
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Immmunogenicity and Structure of trimeric HIV-1 gp120 gl
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批准号:7184287
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Biophysics /Structure /Immunogenicity of HIV-1Glycoprote
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批准号:7189318
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Production And Characterization Of HIV-1 Solid Phase Proteoliposomes
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批准号:7732748
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项目类别:
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资助金额:$41.47万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Determination of the Neutralization Specificity in Broadly Neutralizing HIV Sera
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批准号:7592436
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项目类别:
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资助金额:$19.16万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Administrative Core
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批准号:8829138
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项目类别:
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资助金额:$10.27万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位:
Administrative Core
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批准号:8680626
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项目类别:
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资助金额:$11.26万
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财政年份:--
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负责人:Richard Thomas Wyatt
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依托单位: