Genes important for early brain development are also important for adult brain disease

对早期大脑发育很重要的基因对成人脑部疾病也很重要

• 批准号: nhmrc : 1043290
• 负责人: Prof Seong-Seng Tan
• 金额: $ 56.7万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genes-important-early-brain-disease/111565
• 关键词: Genes; important; early; brain; development

I committed to understanding of how the brain develops, grows and regenerates. My laboratory is active in finding a cure for brain injury following brain trauma or brain ischemia. I have discovered that the genes that drive neuron migration and wiring in the fetus also function in the adult brain to improve neuron survival and regeneration. Probing the function of these genes will deliver twin benefits in preventing brain disorder in the newborn and treating brain disease in the adult.

我致力于了解大脑如何发育，生长和再生。我的实验室正在积极寻找治疗脑外伤或脑缺血后脑损伤的方法。我发现，在胎儿中驱动神经元迁移和连接的基因在成人大脑中也起着改善神经元存活和再生的作用。探索这些基因的功能将在预防新生儿大脑疾病和治疗成人大脑疾病方面带来双重好处。