KNEE STABILITY TRAINING IN INDIVDUALS WITH KNEE OSTEOARTHRITIS

膝骨关节炎患者的膝关节稳定性训练

• 批准号: 7234140
• 负责人: G KELLEY FITZGERALD
• 金额: $ 18.08万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7234140
• 关键词: Address; Anterior; Biomechanics; Blinded; Characteristics; Clinical Trials; Degenerative polyarthritis; Disease; Disease Progression; Effectiveness; Electromyography; Equilibrium; Exercise; Gait; Gastrocnemius Muscle; Individual; Joints; Kinetics; Knee; Knee Osteoarthritis; Length; Limb structure; Lower Extremity; Measures; Motion; Movement; Muscle; Pain; Patient Self-Report; Patients; Pattern; Performance; Physical Function; Physical therapy exercises; Prevention program; Purpose; Quality of life; Randomized; Randomized Clinical Trials; Rate; Reaction; Rehabilitation therapy; Standards of Weights and Measures; Testing; Time; Training; Training Programs; Training Technics; Walking; Weight-Bearing state; age related; base; disability; functional status; improved; kinematics; neuromuscular function; programs

DESCRIPTION (provided by applicant): Traditional exercise therapy programs for knee osteoarthritis (OA) primarily focus on addressing lower extremity strength and joint motion deficits and have yielded fair to moderate improvements in functional status. Recently, there has been increasing evidence that alterations in lower extremity biomechanical factors during weight bearing activities, such as, alterations in movement and muscle activity patterns, ground reaction forces, and lower extremity loading rates, may have substantial impact on functional status and perhaps progression of disease in individuals with knee OA. Based on these findings, it has been suggested that the effectiveness of exercise therapy programs might be improved by incorporating activities that address altered biomechanical factors. We believe that in addition to strength and joint mobility exercises, incorporating balance and agility training techniques (knee stability training) may improve the effectiveness of exercise therapy by inducing favorable changes in lower extremity biomechanics and allowing for greater improvements in functional status than what can be achieved by strength and joint mobility exercise alone. The overall aim of this project is to test the effectiveness of supplementing traditional exercise therapy with knee stability training techniques, tailored for individuals with knee OA, for improving pain, physical function, and lower extremity biomechanics in individuals with knee OA. We will compare individuals with knee OA who receive a standard exercise therapy program (standard group) to those who receive the same standard program, supplemented with knee stability training techniques (stability training group). The study will be a two group, repeated measures, randomized, blinded clinical trial to compare changes in pain, physical function, lower extremity kinematics, kinetics, and electromyography during gait and a step down task, and changes in spatial/temporal characteristics of gait between subjects with knee OA who receive a standard rehabilitation program and those receiving the same standard program that is supplemented with the knee stability training program. The results of this study will assist in determining whether knee stability training techniques are likely to enhance lower extremity biomechanical and neuromuscular function as well as physical performance and disability over standard training techniques in patients with knee OA. Information gained from this study may improve the ability to refine rehabilitation and prevention programs for individuals with knee OA with the purpose of improving the overall quality of life for individuals with this age related progressive disorder.

描述（由申请人提供）：膝关节骨关节炎（OA）的传统运动治疗方案主要关注下肢力量和关节运动缺陷，并已在功能状态方面取得了相当至中度的改善。最近，有越来越多的证据表明，在负重活动过程中下肢生物力学因素的改变，如运动和肌肉活动模式的改变，地面反作用力和下肢负荷率，可能对膝关节OA患者的功能状态和疾病进展产生重大影响。基于这些发现，有人建议，运动治疗计划的有效性可能会提高纳入活动，解决改变生物力学因素。我们认为，除了力量和关节活动性训练外，结合平衡和敏捷性训练技术（膝关节稳定性训练）可以通过诱导下肢生物力学的有利变化来提高运动疗法的有效性，并允许比单独的力量和关节活动性训练更大程度地改善功能状态。本项目的总体目标是测试为膝关节OA患者量身定制的膝关节稳定性训练技术补充传统运动疗法的有效性，以改善膝关节OA患者的疼痛、身体功能和下肢生物力学。我们将比较接受标准运动治疗计划（标准组）和接受相同标准计划并辅以膝关节稳定性训练技术（稳定性训练组）的膝关节OA患者。该研究将是一项两组、重复测量、随机、设盲的临床试验，以比较步态和步下任务期间疼痛、身体功能、下肢运动学、动力学和肌电图的变化，空间变化/接受标准康复计划的膝关节OA受试者与接受补充膝关节稳定性训练的相同标准计划的受试者之间步态的时间特征程序. 本研究的结果将有助于确定膝关节稳定性训练技术是否可能增强膝关节OA患者的下肢生物力学和神经肌肉功能，以及与标准训练技术相比的身体表现和残疾。从本研究中获得的信息可能会提高改善膝关节OA患者康复和预防计划的能力，目的是改善这种年龄相关进行性疾病患者的整体生活质量。

项目成果

Associations for change in physical and psychological factors and treatment response following exercise in knee osteoarthritis: an exploratory study.

• DOI: 10.1002/acr.21751
• 发表时间: 2012-11
• 期刊: ARTHRITIS CARE & RESEARCH
• 影响因子: 4.7
• 作者: Fitzgerald, G. Kelley;White, Daniel K.;Piva, Sara R.
• 通讯作者: Piva, Sara R.

Effects of impairment-based exercise on performance of specific self-reported functional tasks in individuals with knee osteoarthritis.

基于损伤的运动对膝骨关节炎患者自我报告的特定功能任务表现的影响。

• DOI: 10.2522/ptj.20100269
• 发表时间: 2011
• 期刊: Physical therapy
• 影响因子: 3.2
• 作者: Teixeira,PauloEP;Piva,SaraR;Fitzgerald,GKelley
• 通讯作者: Fitzgerald,GKelley

Relationships of fear, anxiety, and depression with physical function in patients with knee osteoarthritis.

• DOI: 10.1016/j.apmr.2009.06.012
• 发表时间: 2009-11
• 期刊: Archives of physical medicine and rehabilitation
• 影响因子: 4.3
• 作者: Scopaz KA;Piva SR;Wisniewski S;Fitzgerald GK
• 通讯作者: Fitzgerald GK

Comparison of reliability and responsiveness of patient-reported clinical outcome measures in knee osteoarthritis rehabilitation.

• DOI: 10.2519/jospt.2012.4038
• 发表时间: 2012-08
• 期刊: The Journal of orthopaedic and sports physical therapy
• 作者: Williams VJ;Piva SR;Irrgang JJ;Crossley C;Fitzgerald GK
• 通讯作者: Fitzgerald GK

Effect of baseline quadriceps activation on changes in quadriceps strength after exercise therapy in subjects with knee osteoarthritis.

膝骨关节炎患者运动治疗后股四头肌基线激活对股四头肌力量变化的影响。

• DOI: 10.1002/art.24650
• 发表时间: 2009
• 期刊: Arthritis and rheumatism
• 作者: Scopaz,KristenA;Piva,SaraR;Gil,AlexandraB;Woollard,JasonD;Oddis,ChesterV;Fitzgerald,GKelley
• 通讯作者: Fitzgerald,GKelley