A Combined in-Vivo/in-Vitro study of Anterior Cruciate Ligament Biomechanics

前十字韧带生物力学的体内/体外联合研究

• 批准号: 341856-2012
• 负责人: Chandrashekar, Naveen
• 金额: $ 1.6万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=527488
• 关键词: Combined; Vivo; Vitro; study; Anterior

About 100,000 young athletes in North America tear their anterior cruciate ligament (ACL) within the knee every year, resulting in more than 2 billion dollars of treatment costs. The mechanism of ACL injury is not well understood because previous studies have been unable to relate knee kinematics during sports activities to the strain in the ACL. Further, no tools are available to identify individuals who are at high risk of ACL injury. Unless the relationship between knee kinematics and ACL strain during high-risk activities is understood, screening of athletes for ACL injury risk and design of injury prevention methodologies is not possible.

北美每年约有10万名年轻运动员膝盖内的前十字韧带（ACL）撕裂，导致超过20亿美元的治疗费用。ACL损伤的机制还没有很好的理解，因为以前的研究已经无法将膝关节运动学在体育活动中的ACL的应变。此外，没有工具可用于识别ACL损伤高风险的个体。 除非在高风险活动期间膝关节运动学和ACL应变之间的关系被理解，否则不可能筛选运动员的ACL损伤风险和设计损伤预防方法。