Manufacturing Research and Development of 2D Electrostrictive Ultrasonic Arrays

二维电致伸缩超声阵列的制造研发

• 批准号: 7326994
• 负责人: Charles Dale Emery
• 金额: $ 16.23万
• 依托单位: ACOUSTX CORPORATION
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7326994
• 关键词: Acoustics; Arrhythmia; Automobile Driving; Clinic; Clinical Research; Development; Devices; Diagnostic; Diagnostic Procedure; Dimensions; Discipline of obstetrics; Drug Formulations; Elements; Elevation; Evaluation; Frequencies; Government; Gynecology; Hemorrhage; Image; Indium; Invasive; Lobe; Location; Manufacturer Name; Marketing; Measures; Mechanics; Medical Imaging; Methods; Numbers; Operative Surgical Procedures; Performance; Persons; Phase; Polychlorinated Biphenyls; Principal Investigator; Process; Purpose; Radiology Specialty; Resistance; Resolution; Side; Signal Transduction; Small Business Funding Mechanisms; Small Business Innovation Research Grant; System; Techniques; Technology; Testing; Therapeutic; Time; Transducers; Ultrasonic Transducer; Ultrasonics; Ultrasonography; United States; Universities; Water; Work; Zebra; base; cost; density; design; electric impedance; experience; falls; malignant breast neoplasm; manufacturing process; novel; prevent; programs; prototype; research and development; response; systems research

DESCRIPTION (provided by applicant): Proposed is the development of manufacturing processes for electrostrictive arrays allowing for real-time ultrasound volumetric imaging. To date, the commercial development of 2D transducer arrays having thousands of array elements has been significantly limited due to manufacturing inefficiencies, transducer element sensitivity; the complexity associated with the driving circuitry and interconnect density. The proposed research and development herein will simplify the interconnects and optimize the beam forming capabilities of the array. AcousTx's experience in novel piezoelectric processing and fabrication techniques will allow for the development of commercially efficient and low cost manufacturing processes. The proposed near term product is a row/column (128 elements by 128 elements) electrostrictive array for volumetric imaging having extensive applications in the fields of radiology, obstetrics and gynecology. Beyond this near term market, lies the potential to combine efficient 2D electrostrictive arrays with the commercially viable and low cost manufacturing processes allowing real time ultrasound large aperture volumetric imaging to become common place in clinics for purposes of i) Advanced non-invasive diagnostic procedures (e.g. breast cancer, internal bleeding, heart arrhythmias etc.), ii) Non-invasive inter-operative guidance for minimally invasive surgery and iii) Combined imaging and therapeutic ultrasound applications. The Phase One effort has the following objectives: i) Develop and optimize the electrostrictive array fabrication processing steps ii) Develop interconnect capability optimized for manufacturing efficiency, iii) Develop beam forming and focusing capabilities in 3D and iv) Evaluate and test a 2D (48 element by 48 element) electrostrictive row/column array prototype. Based upon the successful completion of the Phase One aims, the proposed Phase Two work will be directed towards i) developing/optimizing scalable manufacturing methods to produce a 128 x128 element 2D volume imaging array with a center frequency of 5MHz and ii) packaging the array, design and fabrication of the bias hardware and control circuitry and an iii) internal clinical study to evaluate performance. This proposal is in response to PA-06-013 which is in response to an Executive Order 13329 from the President of the United States placing high priority on SBIR programs directed to Manufacturing Research and Development.

描述（由申请人提供）：建议开发电伸缩阵列的制造工艺，允许实时超声体积成像。迄今为止，由于制造效率低下，传感器元件灵敏度高，具有数千个阵列元件的2D传感器阵列的商业开发受到严重限制；与驱动电路和互连密度相关的复杂性。本文提出的研究和发展将简化互连和优化阵列的波束形成能力。AcousTx在新型压电加工和制造技术方面的经验将有助于开发商业高效和低成本的制造工艺。提议的近期产品是用于体积成像的行/列（128个元素乘128个元素）电伸缩阵列，在放射学，产科和妇科领域具有广泛的应用。除了这个短期市场之外，还存在将有效的二维电伸缩阵列与商业上可行的低成本制造工艺相结合的潜力，从而使实时超声大孔径容积成像在诊所中变得普遍，用于i)先进的非侵入性诊断程序（例如乳腺癌，内出血，心律失常等）；ii)微创手术的无创术间指导iii)影像与超声治疗的联合应用。第一阶段的工作有以下目标：i)开发和优化电致伸缩阵列制造加工步骤ii)开发针对制造效率优化的互连能力iii)开发3D的波束形成和聚焦能力iv)评估和测试2D（48单元× 48单元）电致伸缩行/列阵列原型。基于第一阶段目标的成功完成，拟议的第二阶段工作将针对i)开发/优化可扩展的制造方法，以生产中心频率为5MHz的128 x128元件2D体积成像阵列；ii)封装阵列，设计和制造偏置硬件和控制电路；iii)内部临床研究以评估性能。该提案是对PA-06-013的回应，PA-06-013是对美国总统13329号行政命令的回应，该命令将制造业研究与开发的SBIR项目置于高度优先地位。