Flat-panel X-ray Imaging Detector with Avalanche Gain

具有雪崩增益的平板 X 射线成像探测器

• 批准号: 7261359
• 负责人: Wei Zhao
• 金额: $ 36.95万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-07 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7261359
• 关键词: Address; Area; Biological Models; Breast; Characteristics; Charge; Condition; Coupled; Coupling; Deposition; Depth; Devices; Diagnostic radiologic examination; Digital Mammography; Dose; Electron Beam; Engineering; Erythrocyte Ghost; Experimental Models; Facility Construction Funding Category; Film; Fluoroscopy; Hybrids; Image; Investigation; Light; Measurement; Measures; Methods; Modeling; Morphologic artifacts; Noise; Performance; Procedures; Property; Rate; Reading; Research Design; Selenium; Source; Speed; Structure; Techniques; Technology; Thick; Transistors; Tube; base; cesium iodide; design; detector; diagnostic accuracy; electric field; falls; imaging detector; improved; novel; physical model; prototype; quantum; voltage

DESCRIPTION (provided by applicant): The objectives of this proposal are to demonstrate the feasibility of an indirect flat-panel detector with programmable gain based on structured scintillator - cesium iodide (Csl), avalanche amorphous selenium (a-Se) photoconductor (which we call HARP) with increased gain and active matrix (AM) thin film transistor (TFT) readout, and improve the low dose imaging performance of flat-panel x-ray imaging detectors. We call the detector under investigation SHARP-AMFPI (Scintillator HARP Active Matrix Flat Panel Imager). It will provide better image quality in fluoroscopy, behind dense breasts in mammography, and digital tomosynthesis, where existing flat-panel detectors fall short of quantum noise limitation. Furthermore the inherent high electric field and charge carrier mobility in HARP allows better temporal imaging performance which leads to less image artifacts and better diagnosis accuracy. The specific aims are to: (1) understand and optimize the fundamental imaging properties of Csl and HARP for different x-ray imaging applications; (2) demonstrate the excellent low dose and high speed performance of SHARP using a prototype HARP tube optically coupled to optimized Csl layers; (3) identity potential practical difficulties for constructing SHARP-AMFPI and develop engineering methods for solving them; (4) demonstrate the practical feasibility of the proposed detector. Our research design and methods are to develop experimental and modeling techniques to investigate the fundamental imaging properties of Csl and HARP, verify the validity of models with experimental results so that the model can be used to optimize detector design parameters. We will investigate the feasibility of the detector using three gradual steps: First, the advantage of avalanche gain on image quality will be demonstrated using the matured electron beam readout technology for HARP, then a hybrid prototype detector will be made based on existing TFT array and HARP layer deposition technology so that compatibility issues between these two devices can be fully investigated, and finally a integrated prototype detector will be constructed using procedure that is scalable to large areas to demonstrate the ultimate feasibility of SHARP-AMFPI. Its x-ray imaging performance will be evaluated and compared to existing FPI technologies, so that its improved performance at low dose and high frame rates can be demonstrated.

描述（由申请人提供）： 本提案的目的是证明具有可编程增益的间接平板探测器的可行性，该间接平板探测器基于结构化闪烁体-碘化铯（Csl）、具有增加的增益的雪崩非晶硒（a-Se）光电导体（我们称之为HARP）和有源矩阵（AM）薄膜晶体管（TFT）读出，并改善平板X射线成像探测器的低剂量成像性能。我们将正在研究的探测器称为SHARP-AMFPI（闪烁器HARP有源矩阵平板成像仪）。它将在荧光透视、乳腺X射线摄影和数字断层合成中提供更好的图像质量，现有的平板探测器无法达到量子噪声限制。此外，HARP中固有的高电场和电荷载流子迁移率允许更好的时间成像性能，这导致更少的图像伪影和更好的诊断准确性。具体目标是：（1）理解和优化CsI和HARP的基本成像特性以用于不同的X射线成像应用;（2）使用光学耦合到优化的CsI层的原型HARP管来展示SHARP的优异的低剂量和高速性能;（3）识别构建SHARP-AMFPI的潜在实际困难并开发解决它们的工程方法;（4）论证了所提出的检测器的实际可行性。我们的研究设计和方法是发展实验和建模技术来研究Csl和HARP的基本成像特性，用实验结果验证模型的有效性，以便模型可以用于优化探测器的设计参数。我们将使用三个渐进步骤来研究检测器的可行性：首先，将使用成熟的HARP电子束读出技术来证明雪崩增益对图像质量的优势，然后将基于现有的TFT阵列和HARP层沉积技术制作混合原型探测器，以便可以充分研究这两种器件之间的兼容性问题，最后，将使用可扩展到大面积的过程来构建集成的原型探测器，以证明SHARP-AMFPI的最终可行性。将评估其X射线成像性能，并与现有的FPI技术进行比较，以便证明其在低剂量和高帧率下的性能改进。