Parkinson Disease Neuroprotection Clinical Trial

描述（由申请人提供）：这是一份加入多中心试验合作的申请，以测试帕金森病潜在的神经保护剂。具体的方案和研究设计将由指导委员会制定，所有地点都将遵守。我们是一家由总裁和临床主任，5名调查员，4名研究协调员和1名处理市场营销，患者招募和人力资源的业务管理员组成的研究所。我们已经进行了超过20项临床试验（IB、II、III和IV期），涉及帕金森病的各个阶段和其他神经系统疾病，包括不宁腿综合征、肌张力障碍、震颤、肌阵挛、多发性硬化症和糖尿病神经病变。在涉及帕金森氏症的试验中，我们已经达到和/或超过了入组预期。在其中的6个网站中，我们的注册人数最多，或者在所有网站的注册人数中排名前20%。在我们毗邻橙海岸纪念医疗中心的研究所，我们有六个病人检查室，一个专门用于临床试验的大研究室，一个放血/药物储存/设备的房间，台面离心机，冷冻离心机，心电图机，肌电计，看电影/ x射线的灯箱，肌电图机，一个零下冰柜（-40度），2个冰箱/冰柜，一个候诊室，录像机和电视机。医院旁边有一个带自助餐厅的多层停车场。

DESCRIPTION (provided by applicant): This is an application to join a multi-center trial collaboration to test potential neuroprotective agents in Parkinson's disease. The specific protocol and study design will be developed by the steering committee by which all sites will abide. We are a Research Institute consisting of a President and Clinical Director, 5 Investigators, 4 Research Coordinators and 1 Business Administrator who handles marketing, patient recruitment and human resources. We have conducted over 20 clinical trials (Phases IB, II, III and IV) involving various stages of Parkinson's disease and other neurological conditions, including Restless Leg Syndrome, dystonia, tremor, myoclonus, multiple sclerosis, and diabetic neuropathy. In the trials involving Parkinson's disease, we have met and/or exceed enrollment expectations. In six of these, we were the highest enroller and/or in the top 20% of all sites regarding enrollment. At our institute location adjacent to the Orange Coast Memorial Medical Center, we have six patient exam rooms, one large research room dedicated to clinical trials, one room for phlebotomy/drug storage/equipment, countertop centrifuge, refrigerated centrifuge, ECG machine, sphingmometers, light box for viewing films/X-rays, EMG machine, one subzero freezer (-40 degrees), 2 refrigerator/freezers, a waiting room, video, and television. There is a mutli-level parking facility next to the hospital with cafeteria.