Parkinson Disease Neuroprotection Clinical Trial

描述（由申请人提供）：这是一份加入多中心试验合作的申请，旨在测试帕金森病的潜在神经保护剂。具体方案和研究设计将由指导委员会制定，所有研究中心均应遵守。我们是一家研究机构，由一名总裁兼临床总监，5名研究员，4名研究协调员和1名负责营销，患者招募和人力资源的业务管理员组成。我们已经进行了20多项临床试验（IB、II、III和IV期），涉及帕金森病和其他神经系统疾病的各个阶段，包括不宁腿综合征、肌张力障碍、震颤、肌阵挛、多发性硬化和糖尿病神经病变。在涉及帕金森病的试验中，我们达到和/或超过了招募预期。在其中6个研究中心中，我们是最高的入组者和/或在所有研究中心的入组率前20%。我们的研究所位于橙子海岸纪念医学中心附近，我们有六个患者检查室，一个大型研究室专门用于临床试验，一个用于静脉切开术/药物储存/设备的房间，台式离心机，冷冻离心机，心电图机，鞘氨醇计，用于查看电影/X射线的灯箱，EMG机，一个零度以下的冷冻室（-40度），2个冰箱/冰柜，一个等候室，视频和电视。医院旁边有一个多层停车场，设有自助餐厅。

DESCRIPTION (provided by applicant): This is an application to join a multi-center trial collaboration to test potential neuroprotective agents in Parkinson's disease. The specific protocol and study design will be developed by the steering committee by which all sites will abide. We are a Research Institute consisting of a President and Clinical Director, 5 Investigators, 4 Research Coordinators and 1 Business Administrator who handles marketing, patient recruitment and human resources. We have conducted over 20 clinical trials (Phases IB, II, III and IV) involving various stages of Parkinson's disease and other neurological conditions, including Restless Leg Syndrome, dystonia, tremor, myoclonus, multiple sclerosis, and diabetic neuropathy. In the trials involving Parkinson's disease, we have met and/or exceed enrollment expectations. In six of these, we were the highest enroller and/or in the top 20% of all sites regarding enrollment. At our institute location adjacent to the Orange Coast Memorial Medical Center, we have six patient exam rooms, one large research room dedicated to clinical trials, one room for phlebotomy/drug storage/equipment, countertop centrifuge, refrigerated centrifuge, ECG machine, sphingmometers, light box for viewing films/X-rays, EMG machine, one subzero freezer (-40 degrees), 2 refrigerator/freezers, a waiting room, video, and television. There is a mutli-level parking facility next to the hospital with cafeteria.