Direct printing of functionalised nanoscale polymeric membranes
直接印刷功能化纳米级聚合物膜
基本信息
- 批准号:2889518
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:英国
- 项目类别:Studentship
- 财政年份:2023
- 资助国家:英国
- 起止时间:2023 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Chemical separations are critical to almost all aspects of daily life, with separation processes consuming 10-15% of the world's total energy usage. It is estimated that highly selective membranes could make these processes 10-times more energy efficient, saving 100 million tonnes/year of carbon dioxide emissions and £3.5 billion in energy costs annually (US DoE). More selective separations will help to "maximise the advantages for UK industry from the global shift to clean growth" and will assist in the transition towards "low carbon technologies and the efficient use of resources" (HM Govt Clean Growth Strategy, 2017). In the area of liquid separations, such as water filtration or pharmaceutical production, there are significant unmet challenges which can be tackled by more selective membrane processes. In the water sector, there are difficulties in removal of ions and small molecules at very low concentrations, so called micropollutants (Cave Review, 2008). In pharmaceutical production, there is an unmet need for highly selective separation of product-related impurities, such as active from inactive viruses (HM Govt Industrial Strategy 2017). Novel separation approaches are also required by those developing sustainable approaches to chemical manufacture for removing small amounts of potent inhibitors during feedstock production. Manufacturers of high-value products would therefore benefit from higher recoveries offered by more selective membranes.The aim of this project therefore is to improve selectivity and longevity of membranes in water filtration. To achieve this, the following objectives are set:Year 1, membrane fabrication:Use porogens within ink mixtures to print porous structures.Optimise ink mixtures for printing of nanoscale membranes.Establish optimal printing parameters and procedures for production of nanoscale membranes.Year 2, optimisation of membrane performance:Evaluate filtration performance of printed membranes using crossflow filtration apparatus.Incorporate functionalisation into ink mixture and subsequent membranes.Optimise module design with respect to mixing and pressure drop.Perform a life cycle assessment of printed membranes and compare to comparable commercial membranes.Year 3, assessment and evaluation of industrial applications:Evaluate filtration performance of custom ink mixtures under real world conditions and applications.Using water matrices from local water utilities, e.g.: Wessex water, Bristol water, Southwest waterConsider module design for production scale up.
化学分离对日常生活的几乎所有方面都至关重要,分离过程消耗了世界总能源使用量的10-15%。据估计,高选择性膜可以使这些过程的能效提高10倍,每年节省1亿吨二氧化碳排放量和35亿英镑的能源成本(美国能源部)。更有选择性的分离将有助于“最大限度地发挥英国工业从全球向清洁增长转变中的优势”,并将有助于向“低碳技术和有效利用资源”过渡(HM Govt Clean Growth Strategy,2017)。在液体分离领域,如水过滤或制药生产,存在显著的未满足的挑战,可以通过更具选择性的膜工艺来解决。在水部门,很难去除浓度很低的离子和小分子,即所谓的微污染物(Cave Review,2008年)。在药品生产中,对产品相关杂质(如活性病毒和非活性病毒)的高选择性分离需求尚未得到满足(HM Govt Industrial Strategy 2017)。那些开发可持续的化学制造方法的人也需要新的分离方法,以在原料生产过程中去除少量的有效抑制剂。因此,高价值产品的制造商将受益于更高的选择性膜提供的更高的回收率。因此,本项目的目的是提高水过滤膜的选择性和寿命。为了实现这一目标,我们设定了以下目标:第一年,膜制造:在油墨混合物中使用致孔剂打印多孔结构。优化油墨混合物以打印纳米级膜。建立最佳的打印参数和生产纳米级膜的程序。第二年,膜性能优化:使用错流过滤设备评估印刷膜的过滤性能。将功能化纳入油墨混合物和后续膜中。根据混合和压降优化模块设计。对印刷膜进行生命周期评估,并与可比的商业膜进行比较。第3年,工业应用的评估和评价:在真实的世界条件和应用下评价定制油墨混合物的过滤性能。使用来自当地水务公司的水基质,例如:Wessex水、布里斯托水、西南水考虑模块设计以扩大生产规模。
项目成果
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其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
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LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
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2021 - 期刊:
- 影响因子:0
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吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
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