8th International Primary Hyperoxaluria Workshop

描述（由申请人提供）：这是一份申请，要求提供资金，以部分支持2007年6月29日至30日在英国伦敦举行的第八届国际原发性高血压研讨会。这是自1990年以来每2-3年举办一次的系列研讨会中的第8次，上一次研讨会于2004年在明尼苏达州的罗切斯特举行。2007年的会议将是该研讨会首次在伦敦举行，尽管这座城市在20世纪80年代、90年代和21世纪初是PH研究进展的中心。虽然这些讲习班在开始时具有明显的欧洲性质，但现在已经发展成为真正的国际性质。预计与会者将来自地球仪的各个角落，包括欧洲、北美、澳大拉西亚和亚洲。这些研讨会是目前临床医生，临床科学家和基础科学家聚集在一起讨论遗传性高尿症和草酮糖症的最新实验室发现以及如何将其迅速转化为临床管理的改进的唯一机会。在过去的15年里，我们对原发性高尿酸血症的分子病因学和病理生理学的理解取得了巨大的进步，部分原因是在这些研讨会上进行了令人兴奋的讨论和互动。一个专门为患者，家人和朋友设计的会议包括为这些人提供的机会，他们都以某种方式受到PH的影响，与研究这种疾病的科学家交流。目前，在25名科学/临床特邀发言者中，有9名来自美国，但预计将有更多的美国科学家，特别是年轻的研究人员参加讨论，并在简短的口头报告或海报会议上介绍他们的工作。这一系列双/三年一次的PH研讨会是目前唯一的机会，来自许多不同学科的专家（例如儿科和成人肾脏病学，移植手术，代谢医学，分子和细胞生物学，临床和分子遗传学）讨论他们对原发性高血压的共同兴趣。

DESCRIPTION (provided by applicant): This is an application requesting funds to partially support the 8th International Primary Hyperoxaluria Workshop being held in London, United Kingdom, on June 29 - 30, 2007. This Workshop is the 8th in a series that has run every 2-3 years since 1990 and the previous workshop was held in Rochester, MN in 2004. The meeting in 2007 will be the first time the workshop has been held in London, even though this city was at the center of the advances in PH research in the 1980s, 1990s, and early 2000s. Although at the beginning these workshops were decidedly European in nature, they have now evolved to become truly international in character. Participants are expected from all corners of the globe, including Europe, North America, Australasia and Asia. These workshops are the only opportunity currently available for clinicians, clinical scientists and basic scientists to get together to discuss the latest laboratory findings in the hereditary hyperoxalurias and oxaloses and how they might be speedily translated into improvements in clinical management. The tremendous advances in our understanding of the molecular etiology and pathophysiology of the primary hyperoxalurias over the past 15 years have been in part due to the stimulating discussions and interactions that have taken place at these workshops. A session specifically designed for patients, families and friends is included and opportunities for these individuals, who are all affected by PH in one way or another, to intermingle with the scientists who research this disease are built into the program. Presently, of the 25 scientific/clinical invited speakers, 9 are from the United States, however, it is expected that many more American scientists, especially young investigators, will participate in the discussions and present their work in short oral presentations or in the poster sessions. This series of bi/triennial PH workshops is the only opportunity currently available for specialists from many different disciplines (e.g. pediatric and adult nephrology, transplant surgery, metabolic medicine, molecular and cell biology, clinical and molecular genetics) to discuss their common interest in Primary Hyperoxaluria.