2007 Red Cells Gordon Research Conference

2007 红细胞戈登研究会议

• 批准号: 7328473
• 负责人: JON S MORROW
• 金额: $ 1.75万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-18 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7328473
• 关键词: Affect; Area; Biogenesis; Cell Maturation; Cell Membrane Structures; Cellular biology; Characteristics; Clinical; Clinical Research; Collaborations; Cytoskeletal Proteins; Depth; Development; Diamond-Blackfan anemia; Discipline; Disease; Erythrocytes; Erythroid; Erythropoiesis; Event; Fanconi' s Anemia; Fostering; Gene Expression; Gene Expression Regulation; Hematopoiesis; Individual; Malaria; Membrane; Membrane Proteins; Play; Process; Proteins; Regulation; Regulator Genes; Research; Research Personnel; Role; Scientist; Signal Transduction; Stem cells; Translating; erythroid differentiation; interest; lectures; planetary Atmosphere; posters; symposium; transcription factor

DESCRIPTION (provided by applicant): The Red Cell Gordon Conference has provided an informal atmosphere for in-depth discussions on topics related to red cell biology, regulation of erythroid gene expression, hematopoiesis, and clinically related issues. The meeting, which is consistently oversubscribed, draws leading scientists and clinicians from around the world. The 2007 meeting should be especially noteworthy, given the major recent advances in several of the prominent areas. Nine individual sessions are planned. All will feature a short introductory lecture, followed by a topical keynote and four or five full lectures, and one or two shorter talks provided by trainees or junior investigators or late-breaking discoveries of major significance. A new component of this Gordon Conference will be an entire session devoted to a conferee-wide discussion of how the gene-regulatory events guiding erythroid stem-cell maturation are translated into the phenotypic transitions characteristic of this process. We anticipate that this will be a particularly timely and lively discussion that will draw on the broad expertise of all in attendance, from those studying gene regulation to those studying membrane structure and biogenesis. Other major topics include several clinical disorders, from malaria to rare but poorly understood and important diseases affecting the red cell, such as PNH, Diamond Blackfan anemia, and Fanconi's anemia. The session topics are: Session 1. Developmental aspects of hematopoiesis; Session 2. Membrane-cytoskeletal protein interactions; Session 3. Global regulation of gene expression; Session 4. Transcription factors; Session 5. Control of protein diversity during erythropoiesis; Session 6. Signaling in mature and developing red cells; Session 7. Phenotypic transition during erythroid differentiation Session 8. Red cell membrane structure and dynamics; Session 9. Red cell disorders. Afternoon poster sessions will feature a mix of presentations from all disciplines. The diversity of scientific approaches/interests combined with the richness of discussions of previous Red Cell Gordon Conferences has led to numerous productive collaborations and fostered new developments in basic and clinical research. It is also noteworthy that many of our most fundamental understandings of proteins, membranes, cell biology, and many diseases began with studies in the red cell. The Red Cell Gordon Conference has played a major role in fostering these advances. The 2007 conference will continue this tradition.

描述（由申请人提供）： 红细胞戈登会议提供了一个非正式的气氛，深入讨论有关红细胞生物学，红细胞基因表达调控，造血和临床相关问题的主题。该会议吸引了来自世界各地的顶尖科学家和临床医生。2007年会议应特别值得注意，因为最近在几个突出领域取得了重大进展。计划举办9次单独会议。所有课程都将有一个简短的介绍性讲座，然后是一个主题演讲和四到五个完整的讲座，以及一个或两个由学员或初级研究人员或具有重大意义的最新发现提供的简短讲座。这次戈登会议的一个新组成部分将是一个完整的会议，专门讨论如何引导红系干细胞成熟的基因调控事件转化为这一过程的表型转变特征。我们预计，这将是一个特别及时和生动的讨论，将借鉴所有与会者的广泛专业知识，从那些研究基因调控的人到那些研究膜结构和生物发生。其他主要议题包括几种临床疾病，从疟疾到罕见但知之甚少的重要疾病， 影响红细胞的疾病，如PNH、Diamond Blackfan贫血和Fanconi贫血。会议主题为：会议1。造血发育方面;第2次会议。膜-细胞骨架蛋白相互作用;第3次会议。基因表达的全球调节;会议4。转录因子;会议5。红细胞生成过程中蛋白质多样性的控制;第6节。成熟和发育中的红细胞信号传导;第7节。红系分化过程中的表型转变 第8次会议。红细胞膜结构和动力学;会议9。红细胞疾病。下午的海报会议将包括来自所有学科的演讲。科学方法/兴趣的多样性与以前的红细胞戈登会议的丰富讨论相结合，导致了许多富有成效的合作，并促进了基础和临床研究的新发展。同样值得注意的是，我们对蛋白质、膜、细胞生物学和许多疾病的许多最基本的理解都始于对红细胞的研究。红细胞戈登会议在促进这些进步方面发挥了重要作用。2007年的会议将继续这一传统。