Gordon Research Conference: Collagen 2007

描述（由申请人提供）：这是2007年戈登胶原蛋白研究会议部分支持的申请。2007年会议将于7月22日至27日在新罕布什尔州新伦敦的科尔比-索耶学院举行。2007年的高登胶原蛋白研究会议将是这个两年一度的会议的第36周年，会议的重点是胶原蛋白作为细胞外基质的主要组成部分。它为在结缔组织病理生物学方面有共同兴趣的国际科学家小组提供了一个独特的互动论坛。细胞外基质研究的重大发现通常是在这个会议上首次报道的，涉及胶原蛋白的基础生物学、发育和疾病。2007年会议将强调关于细胞外基质和细胞内胶原相互作用的新信息；细胞外基质的功能和组装；胶原蛋白基因组结构；胶原蛋白比较基因组学；蛋白质的翻译后加工；在发育过程中编码这些蛋白质的基因的调控；胶原蛋白在组织工程和再生医学中的应用以及作为基因治疗靶点的研究以及人类和模式生物中胶原蛋白突变或基因缺失的表型和代谢后果。国际公认的结缔组织生物学家以及崭露头角的研究人员将被邀请介绍目前在该领域的前沿工作。会议为在现有科学家之间以及在现有科学家和新科学家之间发展富有成效的合作提供了宝贵的机会；这些合作反过来又进一步促进了该领域的科学进步。

DESCRIPTION (provided by applicant): This is an application for partial support of the Gordon Research Conferences on Collagen in 2007. The 2007 Conference will be held at Colby-Sawyer College in New London, NH, July 22th to 27th. The 2007 Collagen Gordon Research Conference will be the 36th anniversary of this biennial conference focused on collagens as key continents of extracellular matrix. It provides a unique forum for interaction of an international group of scientists with common interests in the pathobiology of connective tissues. Major discoveries in extracellular matrix research are often reported for the first time at this conference in the basic biology, development, and diseases involving collagen. The 2007 conference will emphasize new information regarding the interactions of collagens within extracellular matrices and with cells; the function and assembly of the extracellular matrix; structure of the collagen genome; comparative genomics of collagen; postranslational processing of proteins; the regulation of genes encoding these proteins during development; collagen in tissue engineering and regenerative medicine and as a target for gene therapy; and the phenotypic and metabolic consequences of collagen mutations or gene deletion in humans and model organisms. Internationally recognized connective tissue biologists as well as up-and-coming investigators will be invited to present current work at the forefront of the field. The Conference has provided an invaluable opportunity for development of productive collaborations among established scientists and between established and new scientists; those collaborations have in turn, further enhanced the scientific progress in the field.