Biennial Symposium on H.ducreyi Pathogenesis & Chancroid

杜克雷嗜血杆菌引起生殖器溃疡疾病软下疳，一直被忽视为人类疾病的重要原因，直到20世纪80年代，软下疳被发现是HIV异性传播的主要辅助因素。1991年，两年一度的H. ducreyi发病机制和软下疳是与国际性病研究学会（ISSTDR）国际会议同时举行的。会议的目的是促进在治愈方面的进展，以迅速了解这种被忽视的病原体的生物学和流行病学，并制定根除软下疳的战略。螺杆杜克雷伊专题讨论会是国际空间技术减灾战略的一个卫星专题讨论会，每两年举行一次，在北美和欧洲轮流举行。这一具体建议是要求提供资金， 协助赞助H. ducreyi研讨会，特别是部分承担研究生，博士后研究员和教师演讲者参加下三次会议的差旅费。第八届和第九届国际研讨会将分别在阿姆斯特丹和西雅图举行，第十届会议的地点尚未确定。研讨会的主要目的是提供一个论坛，交流有关软下疳研究的临床和基础方面的信息，并为学生，博士后研究员和新的研究人员提供机会，介绍他们对这种生物体的研究。在绑H。ducreyi专题讨论会ISSTDR会议，我们为与会者提供互动的能力， 临床医生、流行病学家、公共卫生人员和从事广泛的性病研究领域的基础科学家。会议还促进了美国研究人员与软下疳流行的发展中国家研究人员之间的互动。我们的目标是鼓励H. ducreyi和软下疳在发病机制、宿主反应、疫苗开发、HIV和H. ducreyi相互作用，流行病学和疾病根除。 来自NIAID的Melton埃尔南德斯博士的批准函见本申请第33页。

Haemophilus ducreyi, which causes the genital ulcer disease chancroid, had been overlooked as a significant cause of human disease until the 1980's, when chancroid was found to be a major co-factor in the heterosexual transmission of HIV. In 1991, the first in a series of biennial International Symposia on H. ducreyi Pathogenesis and Chancroid was held in conjunction with the International Society for STD research (ISSTDR) International Meeting. The purpose of the meeting was to promote progress in curability to rapidly to understand the biology and epidemiology of this neglected pathogen and to devise strategies to eradicate chancroid. The H. ducreyi symposium is a satellite symposium of the ISSTDR, which meets every two years, alternating between North America and Europe. This specific proposal is to request funds to assist in sponsoring the H. ducreyi symposium, specifically to partially underwrite the expense of travel of graduate students, postdoctoral fellows, and faculty presenters to the next three iterations of the meeting. The 8th and 9th International Symposia will be held in Amsterdam and Seattle respectively; the venue for the 10th meeting has not been determined. The major objective of the Symposium is to provide a forum for exchange of information on clinical and basic aspects of chancroid research, and to provide the opportunity for students, post-doctoral fellows and new investigators to present their research on this organism. In tying the H. ducreyi symposium to the ISSTDR meeting, we provide participants the ability to interact with clinicians, epidemiologists, public health personnel and basic scientists who work in the broad area of STD research. The meeting also fosters interaction between investigators from the United States with those from developing countries where chancroid is endemic. Our goal is to encourage basic and clinical research in the biology of H. ducreyi and chancroid in the areas of pathogenesis, host responses, vaccine development, HIV and H. ducreyi interactions, epidemiology, and disease eradication. An approval letter from Dr. Melton Hernandez, from the NIAID can be found on page 33 of this application.