Molecular and Cellular Biology of Lipids

脂质的分子和细胞生物学

• 批准号: 7060038
• 负责人: CHARLES E MARTIN
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7060038
• 关键词: ATP-Binding Cassette Transporters; Academy; Air; Animals; Area; Arts; Binding; Biochemistry; Biological; Cell membrane; Cell physiology; Cells; Cellular biology; Chemistry; Cholesterol Homeostasis; Communities; Complex; Coupled; Data; Development; Diabetes Mellitus; Disabled Persons; Emerging Technologies; Ensure; Environment; Enzymatic Biochemistry; Equilibrium; Evaluation; Fatty Acids; Fertilization; Funding; Future; Gene Expression; Grant; Homeostasis; Housing; Individual; Letters; Lipid Biochemistry; Lipids; Lipoproteins; Logistics; Longevity; Membrane; Membrane Lipids; Metabolism; Methods; Microbe; Minority; Molecular; Molecular Biology; Molecular and Cellular Biology; Monitor; New Hampshire; Nonprofit Organizations; Obesity; Participant; Performance; Personal Satisfaction; Phospholipase; Phospholipid Metabolism; Phospholipids; Positioning Attribute; Progress Reports; Proteins; Range; Rate; Recording of previous events; Regulation; Research; Research Design; Research Personnel; Resolution; Role; Schedule; Science; Scientific Advances and Accomplishments; Scientist; Signal Transduction; Signaling Molecule; Site; Sterols; Structural Biochemistry; Structure; Students; System; Thinking; Transgenes; Transportation; Triglycerides; Woman; catalyst; concept; design; fatty acid biosynthesis; frontier; handicapping condition; knockout gene; lectures; lipid metabolism; lipid transport; novel; posters; sensor; success; symposium; theories

This application is for partial support of the 2005 and 2007 Gordon Research Conferences on Molecular and Cellular Biology of Lipids. These meetings bring together the leading scientists in the field to present and evaluate their latest research and are designed to stimulate the application of emerging technologies to the frontiers of lipid research. This conference has been held in odd years for over 45 years and is recognized internationally as the most prestigious forum for the presentation of the latest and most significant research in the area of lipid biochemistry and molecular biology. The 2005 meeting, which will be held July 15 to July 20 at Kimball Union Academy, Meriden, NH will continue this tradition of emphasis on the enzymology, biochemistry, and cell biology of lipids, and will include newly emerging information on the role of lipid metabolism in obesity and diabetes, the regulation of lipid homeostasis by membrane bound sensors, and novel molecular mechanisms for intra- and intercellular lipid transport. Nine lecture sessions will be supplemented by afternoon poster sessions in which all participants will be encouraged to present their latest findings. The lecture sessions will cover the following topics: lipid homeostasis, interorganelle lipid transport, metabolites of fatty acids, triacylglycerol metabolism, obesity and diabetes, phospholipid metabolism, ABC transporters and transbilayer lipid flux, cholesterol metabolism, fatty acid biosynthesis, and regulation of lipid metabolism. The speakers will cover a broad spectrum of experimental methods and systems that span from whole animals to eukaryotic and prokaryotic microbes. These include mammalian transgenes and gene knockouts, bioinformaticsstrategies, protein structural biochemistry, enzymology, nmr, crystallographic and state-of-the-art, high resolution spectroscopic methods. These presentations have a history of stimulating lively interdisciplinary discussions among participants who include biochemists, biophysicists, cell biologists and geneticists. Participants of our past conferences have greatly benefited from the cross fertilization of ideas that emerge from these diverse experimental backgrounds and we believe this has contributed greatly to the recent advances in this important area of biochemistry, cell biology, andphysiological chemistry. Participants and speakers will be selected to reflect internationalexcellence in this area of research with an appropriate balance ensuring representation of young scientists, women, and minorities. Proper facilities are available to accommodate handicapped individuals who will be considered equally in the selection of attendees and speakers.

此申请是部分支持2005年和2007年戈登研究会议的分子和细胞 脂质生物学这些会议汇集了该领域的领先科学家，介绍和评估他们的最新成果。 研究和旨在刺激新兴技术的应用，脂质研究的前沿。这 会议已在奇数年举行了超过45年，是国际公认的最负盛名的论坛 介绍脂质生物化学和分子生物学领域最新和最重要的研究。 2005年的会议将于7月15日至7月20日在新罕布什尔州梅里登的金博尔联合学院举行，会议将继续进行 传统的重点是酶学，生物化学和细胞生物学的脂质，并将包括新出现的 关于脂质代谢在肥胖和糖尿病中的作用的信息，通过膜调节脂质稳态 结合传感器，以及细胞内和细胞间脂质转运的新分子机制。九个讲座将 下午的海报会议将作为补充，鼓励所有参与者展示他们最新的 调查结果。讲座将涵盖以下主题：脂质稳态，细胞器间脂质转运， 脂肪酸代谢物、三酰甘油代谢、肥胖和糖尿病、磷脂代谢、ABC转运蛋白 以及跨双层脂质通量、胆固醇代谢、脂肪酸生物合成和脂质代谢的调节。的 演讲者将涵盖从整个动物到真核生物的广泛的实验方法和系统 和原核微生物。这些包括哺乳动物转基因和基因敲除，生物信息学策略，蛋白质 结构生物化学、酶学、NMR、晶体学和最先进的高分辨率光谱方法。 这些演讲有一个历史，刺激活跃的跨学科讨论的参与者，其中包括 生物化学家、生物药理学家、细胞生物学家和遗传学家。我们过去会议的参与者受益匪浅 从这些不同的实验背景中产生的想法的交叉受精中，我们相信这已经 对生物化学、细胞生物学和生理学这一重要领域的最新进展作出了巨大贡献。 化学.与会者和发言者将被选择，以反映在这一研究领域的国际卓越与 适当平衡，确保青年科学家、妇女和少数群体的代表性。有适当的设施 以容纳残疾人，他们在选择与会者和发言者时将得到平等考虑。