Rapid metagenomic strain profiling of inflammatory bowel disease (IBD) patients via Nanopore sequencing

通过纳米孔测序对炎症性肠病 (IBD) 患者进行快速宏基因组菌株分析

• 批准号: 2894010
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2894010
• 关键词: Rapid; metagenomic; strain; profiling; inflammatory

The project will explore changes in the gut microbiome of patients with Inflammatory Bowel Disease (IBD), combine high-resolution metagenomics with 3rd generation sequencing, develop experimental and bioinformatic protocols to distinguish specific gut bacterial strains that can be associated to IBD, and explore their potential impact on the human host.

该项目将探索炎症性肠病（IBD）患者肠道微生物组的变化，将高分辨率宏基因组学与第三代测序相结合，制定实验和生物信息学方案，以区分可能与IBD相关的特定肠道细菌菌株，并探索它们对人类宿主的潜在影响。