Ethical Issues Regarding Women in Health Research

健康研究中有关女性的伦理问题

• 批准号: 7166094
• 负责人: ANNE Drapkin LYERLY
• 金额: $ 10.26万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-12-17 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7166094
• 关键词: Affect; Area; Attitude; Automobile Driving; Award; Belief; Bioethics; Bioethics Consultants; Clinical Research; Counseling; Couples; Cryopreservation; Data; Depth; Development; Discipline of obstetrics; Education; Educational process of instructing; Embryo; Ethical Issues; Ethics; Faculty; Family; Fellowship; Fertilization; Fertilization in Vitro; Freezing; Future; General Population; Genetic; Genetic Research; Genome; Germ Cells; Goals; Gynecology; Health; Health Personnel; Healthcare; Humanities; In Vitro; Individual; Institution; Interview; Knowledge; Laws; Lead; Legal Status; Mediation; Medical Ethics; Mentors; Mentorship; Methods; Nature; Pattern; Policies; Policy Maker; Qualitative Methods; Qualitative Research; Range; Religion and Spirituality; Reproductive Health; Research; Research Design; Research Ethics; Research Methodology; Research Personnel; Scientist; Services; Stem Cell Research; Stem cells; Surveys; Tissue Donors; Training; United States; Universities; Voice; Woman; Women' s Health; Work; authority; base; cooking; embryo tissue; experience; men; professor; programs; reproductive

DESCRIPTION (provided by applicant): The use of embryonic tissue for stem cell and genetic research raises numerous controversial ethical questions. However, little information exists about how decisions regarding such research specifically affect those women from whose gametes the embryos were created and their partners and families. This revised application for a Mentored Scientist Development Award in Research Ethics proposes a five-year course of study to investigate the impact of such new research methods on women. Dr. Lyerly completed a Greenwall Fellowship in Bioethics and Heath Policy at Johns Hopkins and Georgetown in 2001 and is now an Assistant Professor of Obstetrics and Gynecology at Duke University. Based on work she initiated at the National Bioethics Advisory Commission, Dr. Lyerly has begun collecting qualitative data through in-depth interviews on the attitudes of women who have undergone in vitro fertilization regarding potential research on their own cryopreserved embryos. Under the co-mentorship of nationally recognized leaders in research ethics, qualitative methods, and reproductive health, Drs. James Tulsky and Robert Cook-Deegan of Duke University and Dr. Ruth Faden of Johns Hopkins University, Dr. Lyerly proposes to use the observations of these qualitative data to formulate and validate a quantitative survey that will be distributed nationally and assess attitudes of individuals regarding their own cryopreserved embryos. The long-term goal of these studies will be to determine how genetic and stem cell research specifically impacts the women who serve as tissue donors. This is a group whose voice has not yet been introduced into this debate. Dr. Lyerly also proposes a rigorous course of study to further prepare her to be a leader as an empirical researcher in the ethics of reproductive healthcare. She will complete formal research methods training through the Master's program in clinical research at Duke. She will participate as a Faculty Associate at the Center for the Study of Medical Ethics and Humanities and continue work in the Center for Genome Ethics Law and Policy and the Center for Women's Studies. This proposal will support education, teaching and mentored research for the further development of a well-trained bioethicist focused on ethical issues regarding the impact of contemporary and future research on women.

描述（由申请人提供）：使用胚胎组织进行干细胞和遗传研究提出了许多有争议的伦理问题。但是，几乎没有关于有关此类研究的决策如何特别影响那些创建胚胎及其伴侣和家庭的女性的信息。这项修订的申请在研究伦理学中获得的指导科学家发展奖提出了为期五年的研究课程，以研究这种新研究方法对妇女的影响。 Lyerly博士于2001年在Johns Hopkins和Georgetown完成了绿墙奖学金，现在是杜克大学的妇产科助理教授。根据她在国家生物伦理学咨询委员会发起的工作，Lyerly博士已经开始通过深入的访谈收集定性数据，该访谈对妇女的态度，这些妇女的态度对自己的冷冻保存胚胎进行了潜在的研究。在研究伦理学，定性方法和生殖健康领域的全国认可领导人的同事下。杜克大学的詹姆斯·塔尔斯基（James Tulsky）和罗伯特·库克·迪根（Robert Cook-Deegan）以及约翰·霍普金斯大学（Johns Hopkins University）的露丝·法登（Ruth Faden）博士Lyerly博士建议使用这些定性数据的观察来制定和验证定量调查，该调查将在全国范围内分发，并评估个人对自己冷冻保存的胚胎的态度。这些研究的长期目标是确定遗传和干细胞研究如何特异性影响作为组织供体的妇女。这是一个尚未将声音引入此辩论的小组。 Lyerly博士还提出了一项严格的研究课程，以进一步使她成为生殖医疗保健伦理学的经验研究员的领导者。她将通过杜克大学临床研究硕士课程完成正式的研究方法培训。她将在医学伦理和人文研究中心担任教职员工，并继续在基因组伦理法律和政策中心和妇女研究中心工作。该建议将支持教育，教学和指导研究，以进一步发展训练有素的生物伦理学家，重点介绍有关当代和未来研究对妇女的影响的道德问题。