Ethical Issues Regarding Women in Health Research

健康研究中有关女性的伦理问题

• 批准号: 7166094
• 负责人: ANNE Drapkin LYERLY
• 金额: $ 10.26万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-12-17 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7166094
• 关键词: Affect; Area; Attitude; Automobile Driving; Award; Belief; Bioethics; Bioethics Consultants; Clinical Research; Counseling; Couples; Cryopreservation; Data; Depth; Development; Discipline of obstetrics; Education; Educational process of instructing; Embryo; Ethical Issues; Ethics; Faculty; Family; Fellowship; Fertilization; Fertilization in Vitro; Freezing; Future; General Population; Genetic; Genetic Research; Genome; Germ Cells; Goals; Gynecology; Health; Health Personnel; Healthcare; Humanities; In Vitro; Individual; Institution; Interview; Knowledge; Laws; Lead; Legal Status; Mediation; Medical Ethics; Mentors; Mentorship; Methods; Nature; Pattern; Policies; Policy Maker; Qualitative Methods; Qualitative Research; Range; Religion and Spirituality; Reproductive Health; Research; Research Design; Research Ethics; Research Methodology; Research Personnel; Scientist; Services; Stem Cell Research; Stem cells; Surveys; Tissue Donors; Training; United States; Universities; Voice; Woman; Women' s Health; Work; authority; base; cooking; embryo tissue; experience; men; professor; programs; reproductive

DESCRIPTION (provided by applicant): The use of embryonic tissue for stem cell and genetic research raises numerous controversial ethical questions. However, little information exists about how decisions regarding such research specifically affect those women from whose gametes the embryos were created and their partners and families. This revised application for a Mentored Scientist Development Award in Research Ethics proposes a five-year course of study to investigate the impact of such new research methods on women. Dr. Lyerly completed a Greenwall Fellowship in Bioethics and Heath Policy at Johns Hopkins and Georgetown in 2001 and is now an Assistant Professor of Obstetrics and Gynecology at Duke University. Based on work she initiated at the National Bioethics Advisory Commission, Dr. Lyerly has begun collecting qualitative data through in-depth interviews on the attitudes of women who have undergone in vitro fertilization regarding potential research on their own cryopreserved embryos. Under the co-mentorship of nationally recognized leaders in research ethics, qualitative methods, and reproductive health, Drs. James Tulsky and Robert Cook-Deegan of Duke University and Dr. Ruth Faden of Johns Hopkins University, Dr. Lyerly proposes to use the observations of these qualitative data to formulate and validate a quantitative survey that will be distributed nationally and assess attitudes of individuals regarding their own cryopreserved embryos. The long-term goal of these studies will be to determine how genetic and stem cell research specifically impacts the women who serve as tissue donors. This is a group whose voice has not yet been introduced into this debate. Dr. Lyerly also proposes a rigorous course of study to further prepare her to be a leader as an empirical researcher in the ethics of reproductive healthcare. She will complete formal research methods training through the Master's program in clinical research at Duke. She will participate as a Faculty Associate at the Center for the Study of Medical Ethics and Humanities and continue work in the Center for Genome Ethics Law and Policy and the Center for Women's Studies. This proposal will support education, teaching and mentored research for the further development of a well-trained bioethicist focused on ethical issues regarding the impact of contemporary and future research on women.

描述（由申请人提供）：胚胎组织用于干细胞和遗传研究引起了许多有争议的伦理问题。然而，关于这种研究的决定如何具体影响那些从配子中产生胚胎的妇女及其伴侣和家庭的信息很少。这一修订后的研究伦理学指导科学家发展奖申请提出了一个为期五年的研究课程，以调查这种新的研究方法对妇女的影响。Lyerly博士于2001年在约翰霍普金斯和乔治敦完成了生物伦理学和卫生政策的绿墙奖学金，现在是杜克大学的妇产科助理教授。根据她在国家生物伦理咨询委员会发起的工作，Lyerly博士已经开始通过深入采访收集定性数据，了解接受过体外受精的妇女对自己冷冻保存胚胎的潜在研究的态度。在全国公认的研究伦理、定性方法和生殖健康领导者的共同指导下，杜克大学的James Tulsky博士和Robert Cook-Deegan博士以及约翰霍普金斯大学的Ruth Faden博士，Lyerly博士建议使用这些定性数据的观察结果来制定和验证一项定量调查，该调查将在全国范围内分发，并评估个人对自己冷冻保存的态度。胚胎这些研究的长期目标将是确定遗传和干细胞研究如何具体影响作为组织捐赠者的妇女。这是一个尚未在这场辩论中发表意见的群体。Lyerly博士还提出了一个严格的学习课程，以进一步准备她成为生殖保健伦理学的实证研究者。她将通过杜克临床研究硕士课程完成正式的研究方法培训。她将作为医学伦理与人文研究中心的副教授参加，并继续在基因组伦理法律与政策中心和妇女研究中心工作。该提案将支持教育、教学和指导研究，以进一步培养训练有素的生物伦理学家，重点关注当代和未来研究对妇女影响的伦理问题。