Core B - Exposure and Animals

动物暴露和评估核心的总体目标是为研究人员提供支持

The overall goal of the Animal Exposure and Assessment Core is to provide support to investigators studying the impact of oxidant air pollutants on allergic airways disease in infant rhesus monkeys. The Core is housed in the Exposure Facility at the California National Primate Research Center (CNPRC). The Exposure Facility at the CNPRC has well-established facilities for assessing all aspects of exposure to oxidant gases with validated exposure conditions, and has a complete pulmonary function testing unit. Specifically, Core B will: 1. Provide accurate and carefully controlled exposures of animals or in vitro preparations to selected types and concentrations of air pollutants. 2. Develop methods of inhalation exposure and atmosphere characterization. 3. Coordinate purchase, health services and care for experimental animals. 4. Provide logistical and technical support in ensuring experimental regimens are implemented correctly. 5. Collate all exposure and pulmonary function data and to provide this to the experimental units. 6. Coordinate acquisition of tissues at necropsy, and maintain the archive of collections and log of sample custody and storage.